Endovascular treatment of carotid stenosis without protection devices in symptomatic patients aged >75 years is an alternative to endovascular treatment with protection devices. Complications and mortality rates are similar to studies that used protection devices in lower risk patients.
If more than 6 hours have elapsed since the known onset of stroke symptoms, current guidelines for patients set forth by the American Heart Association (AHA) restrict class-IA recommendation to selected patients who have large vessel occlusion (LVO) in the anterior circulation and those cases where images and other eligibility criteria from the DAWN (DWI or CTP Assessment with Clinical Mismatch in the Triage of Wake-Up and Late Presenting Strokes Undergoing Neurointervention with Trevo) and DEFUSE-3 (Endovascular Therapy Following Imaging Evaluation for Ischemic Stroke 3) randomized control trials (RCTs) are strictly applied. 1-3 Ischaemic stroke is a dynamic condition in which the rate and extent of the stroke depend on multiple factors not only correlated
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