Favorable conditions for development, reproduction, and accumulation of large amounts of zoophilous flies in commercial poultry farms are caused by incomplete compliance with veterinary and sanitary rules for growing in cage facilities. The purpose of the study was to test a systematic insecticidal program for destroying flies' populations using adulticide and larvicide drugs in poultry farms under battery cage management. The number of imago flies in hen houses was dynamically evaluated using flypapers, six flypapers in each hen house, situated in different levels above the floor. Flypapers were removed and the number of stuck insects was counted. The number of larvae was evaluated in dynamics by specimen testing from the floor area 10x10 cm, with weight of 3-5 g. The Quick Bayt WG 10% was applied to destroy the imago of flies. Baycidal® WP 25% was used against larvae of flies. Complex insecticide program Quick Bayt WG 10% + Baycidal® WP 25% provided the opportunity to destroy flies, with a significant difference in intensefficacy, (98.3 % for adult flies and 99.8 % for larvae). Furthermore, this program had a positive impact on economic indicators of meat production of broilers. The present study demonstrated high preventive efficacy and economical efficacy of complex program against flies under battery cage broiler management.

We studied the efficacy of Isodez in different concentrations consisting of two active substances and excipients at a dose of 0.5 L/m2 at a 2-hour exposure against Coccidia oocysts in foxes and Arctic foxes in environmental objects. The experiments were performed in the Institute Laboratory and on one of the Moscow Region fur farms in 2019–2020. Under production conditions, the efficacy of Isodez 6% against Coccidia oocysts in the foxes and Arctic foxes was determined by their artificial laying on experimental sites. When the fur animals were artificially infected with these protozoa, the intense-effectiveness (IE) of Isodez was 92.6 and 96.7% at its 5% concentration, 100% at 6% and 7% concentrations, and 64.7–84.5% of the Phenol solution (basic drug) at 5% concentration, respectively. Under the production conditions, the IE of a 6% Isodez solution reached 94.8% at a dose of 0.5 L/m2 and a 2-hour-exposure against Coccidia oocysts in the foxes and Arctic foxes. The results obtained in the experiment and under production conditions make it possible to recommend Isodez consisting of benzalkonium chloride, formaldehyde and surfactants for disinvasion of environmental objects against Coccidia oocysts of the foxes and Arctic foxes.

Scientific and field trials have shown a high intensity of Fasciola hepatica infection in cattle, the recommended dose of the complex preparation of Gelmicidum 7.5 g for every 100 kg of body weight is once inwardly provided extensity of efficacy of 80%, intensity of efficacy of 83.8%. In this case, it was quite justified to increase the therapeutic dose of the drug by 13% and assign 8.5 g/100 kg of b/w, which provided a high extensity of efficacy (EE-100%) and intensity of efficacy (IE-100%). The results of the trials confirmed the previously obtained data on the efficacy EE-96.7%, IE-97.7% of the Gelmicidum preparation in the optimal dose of 8.5 g/100 kg of b/w which corresponds to a dose of 5.95 mg/kg of oxyclosanide and 17 mg/kg of albendazole according to the active substance. Fascocidum revealed 95.6% IE at the recommended dose of 10 mg/kg b/w at single oral administration with feed. The economic effect was 85.9 rubles per cow per day compared to the base variant in the first group (Gelmicidum) and 46.5 rubles in the second (Fascocidum) group. The total economic effect was 154.6 thousand rubles in the group of cows during the experience after treatment (3 months) compared with the base drug in the first group (Gelmicidum) and was 83.7 thousand rubles for the second group (Fascocidum).

Coccidioses (isosporosis, eimeriosis) and balantidiosis are most common among parasitic protozoa in pigs. These parasitoses affect pigs of different ages, but they have the greatest negative effect on the body of young pigs. Piglets of 7–30 days of age are more often infected and more severely ill with isosporosis, and piglets up to 2 months of age and older with eimeriosis. One sow house was taken for testing and constant monitoring. This pigsty was divided into four sectors with 30 sows each. The complex drug Kenokoks 4% at a dose of 0.5 l/m2 with an exposure of two hours was used in the first sector during the preparation of the pigsty for disinfestation. Another complex drug Eimeriocide 5% at a dose of 0.5 l/m2 with an exposure of two hours was used for disinfestation of the second sector. The recommended dose of a 4% hot sodium hydroxide solution was used to disinfection the third and fourth sectors (basic version). The infection of pigs by coccidia in different groups was evaluated according to the results of coproscopic studies in 10, 15, 30, 45 and 60 days of age after completion of the pigsty. The results of coproscopic studies of pigs born from sows from the experimental sector (where disinfestation was performed by Kenokoks) showed that pigs in 10, 15 and 22 days old were free of coccidia oocysts; the extensinfection of coccidia in these piglets at the age of 30, 45 and 60 days was 5, 10 and 20% respectively. Balantidia cyst was found only at 60 days of age, extensinfection was 10%. The pigs were free of coccidia oocysts from the second compartment of the pigsty, where disinfestation was performed with Eimeriocide at 10 and 15 days of age. Infection is set at 22, 30, 45 and 60 days of age, extensinfection was 5, 10, 15 and 20% respectively. Infection with balantidia was established only at 60 days of age; extensinfection was 10%.

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