Antiviral agents were sought by using ethyl esters of 2-R-4-quinolinecarboxylic acids to synthesize the corresponding aryl (heteryl) hydrazides. 2-Methyl-4-quinolinecarboxylic acid hydrazide was used to synthesize vinylogs containing a nitro group in the substituent. The resulting compounds were tested for antiviral activity against ECHO virus type 6. 571 0091-150X/08/4210-0571

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Durch Einwirkung aromatischer und heterocyclischer Aldehyde (I) auf die Hydrazide der entsprechenden Cinchoninsäuren (II) werden die Arylidenhydrazide (III) dargestellt.

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