AIMS: This study aims to estimate the efficacy of Ostene as bone hemostatic agent clinically and experimentally and their effect on the ease of operation in clinical dental practice. MATRIALS AND METHODS: For experimental part: Fifteen males rabbits were divided into three groups according to the time interval for hemostasis measurement, five rabbits in each group. Each group subdivides into other three groups according to study material "ostene, gelfoam, control". On femoral bone, three holes were made. After bleeding started, study material was placed inside holes, then a uniform piece of cotton was applied with gentle pressure, then hemostasis measured using the gravimetric method. For the clinical part: after complete extraction, a piece of study material was implanted inside the tooth socket and covered with uniform cotton for hemostasis, then hemostasis measured using the gravimetric method. RESULTS: For experimental part: study result revealed that the comparison between two local hemostatic agents (ostene and gelfoam) groups for hemostatic effect show Ostene has superiority effect over gelfoam in control bleeding at all interval times. Friedman test revealed a significant difference between study materials P =0.00 (P ≤ 0.05). For the clinical part: clinical measurement, ostene showed significant over gelfoam at 1min, 30 min While there were no significances between ostene and gelfoam at 5min,10min. Regarding visual analog scales for assessing bleeding and ease of operation, ostene, when comparing it with gelfoam, appeared better than gelfoam. CONCLUSIONS: Hemostatic effect of ostene is superior to gelfoam experimentally and after tooth extraction.

Introduction: Implant Dentistry was created to show reliable treatment approaches for restoring the oral cavity’s esthetic and function. However, while dental implants have a high long-term success rate, dental implants are exposed to mechanical or biological complications. Objective: The therapeutic approaches will be addressed in this review, which is the main objective of this study. Materials and Methods: Data sources: The PubMed/MEDLINE, SCOPUS, and Web of Science databases were used to conduct the literature search from June to September 2021. Study selection: Non-surgical and surgical peri-implantitis treatment modalities are the main themes of this study. Result: Implant dentistry was created to show reliable treatment approaches for restoring the oral cavity’s esthetic and function. However, while dental implants have a high long-term success rate, dental implants are exposed to mechanical or biological complications. Conclusion: Peri-implantitis appears to be a multifactorial disease including the patient’s host/microbe response, implant characteristics, soft tissue and the hard conditions surrounding the implant, and the dentist’s surgical and prosthetic part experience. Different treatment modalities are present today, all are used to treat peri-implantitis, such as surgery, laser therapy, and innovative treatments such as cold atmospheric pressure air plasma jet (CAPAJ), enamel matrix derivative, and PRF gel.

Aims:The current study aimed to compare implant stability of dental implants covered with one of twoplatelet rich fibrin preparation protocols namely Standard-Platelet Rich Fibrin and Advanced-Platelet Rich Fibrin) using radiofrequency assessment. Materials and methods: A total of ten male patients with an age range of 28-51 years participated in this split-mouth clinical study. The patients were divided into two groups based on the platelet rich fibrin (PRF) protocol to be used with dental implant insertion into positive control (S-PRF) and study group (A-PRF). Each patient represented the two groups in which he received 2 dental implants; ten implants for each group (a total of 20 dental implants) of standard length and diameter in the posterior mandibular extraction sites of ipsilateral or contralateral side. In the positive control group, the standard PRF protocol was to be used to prepare the PRF clot. In the study group, the advanced PRF protocol was to be used to prepare the PRF clot. Both PRF membranes were to be instilled inside the osteotomy bed during dental fixture installation. Following the installation of dental implants; radiofrequency assessment using Osstell Mentor Device immediately after insertion, four, eight; twelve weeks post-operative as secondary outcomes were conducted. Results: When comparing ISQ means of dental implants between both group protocols, the Friedman test values of ISQ means showed no statistically significant difference between them at the immediate day of surgery, four weeks, eight weeks and twelve weeks post-surgery yet showed increased levels of ISQ at end of the trial. Conclusions: Both S-PRF and A-PRF, similarly enhanced and maintained dental implant stability hence maintain osseointegration (synergistic effect) throughout the period of study and as disclosed by ISQ values. The use of PRF in its current forms seems to be an accepted minimally invasive approach with good clinical results.