IN a previous communication [Macrae et at. 1939] we described the preparation from liver extracts of highly potent concentrates of a nutritional factor for rats to which we applied the name "liver ifitrate factor" [cf. Edgar et al. 1938].; At that time we drew attention to the similarity in properties between this factor and pantothenic acid [Williams et al. 1938; 1939] and discussed the possibility that the two might ultimately prove to be identical. Pantothenic acid was then
Historical brief It seems a far cry from 1761 when the chemist's place ofwork was defined in the following way: 'Laboratory or Elaboratory, the chemists workhouse or the place where they perform their operations, where their furnaces are built, their vessels kept, etc. and in general the term laboratory is applied to any place where physical experiments in pharmacy, chemistry, pyrotechny etc. are performed' [-1]. By 1880 it was pointed out to the American
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