Introduction: Polyps begin as small elevations of the mucosa and polyps are most common in the colorectal region. The neoplastic polyps are important because they have a risk of transformation into malignancy. The role of the Pathologist is to identify any dysplastic changes and inform the clinician regarding the risk of development of carcinoma. Materials and Methods: This is a retrospective analysis of polyps and polypoid lesions of 5 year duration from January 2013 to December 2017. The biopsies were stained with Haematoxylin & Eosin and studied under light microscope. Results: 107 cases of gastrointestinal polyps and polypoid lesions were included in our study. Hyperplastic polyps were the most common polyps found in our study. The most common site was rectum and stomach. Variety of lesions included in our study are multiple Peutz Jeghers (PJ) polyps, adenocarcinoma arising in PJ polyp, neuroendocrine tumours, and an angiomatous polyp. Conclusion: Gastrointestinal polyps are divergent lesions. Differentiation of neoplastic polyps from non-neoplastic polyps is important in view of adenoma-carcinoma sequence developing in neoplastic polyps. Identification of hamartomatous polyps is also crucial since they are associated with syndromes and may unusually transform in to cancers. Pathologists play a key role in diagnosis of neoplastic polyps and polyps associated with syndromes. In our study hyperplastic polyps were most common with a variety of other lesions.

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Background: Blood transfusion is an important,integral and life saving procedure but simultaneously, carries risk of transmitting Transfusion Transmissible Infections(TTIs).The present study was done to find out the seroprevalence and changing trends of various TTIs among blood donors.Methods: Blood donors who attended our blood bank during May 2014 to May 2019 and fulfilled uniform guidelines approved by National blood transfusion council were included. Data regarding type of donors, sex and screening test results were collected from the records.Result: Out of 32046 donors, voluntarydonors(76.3%) were more in comparison to replacement donors(23.7%) and out of 32046, 31944(99.7%) were males and 102(0.3%) were females.Amongst TTIs, seroprevalence of HBV(1.3%) was highest in the blood donors followed by HCV(0.65%),HIV (0.29%),Syphilis (0.06%) and Malaria(0.006%). TTIs were more seroprevalent in replacement donors than voluntary donors. Conclusion:TTIs were more in replacement donors than voluntary donors. A decreasing trend in the seropositivity percentage of most of the TTIs was seen due to strict donor selection criteria and counselling of blood donors. Stringent screening, implementation of more sensitive tests like Nucleic acid amplification test/Chemiluminescent assay and public awareness programs are needed to improve the prevention of TTIs.