Aims: To report further cases of solitary necrotic nodule ofthe liver and to study its nature.Methods: Seven nodules were retrieved from 4000 necropsy and surgical liver specimens coming to light over the past five years. All of them satisfied the diagnostic criteria of solitary necrotic nodule: a solid lesion with a central necrotic core and a hyalinised fibrotic capsule containing elastic fibres. Their clinicopathological features were reviewed. Results: The nodules were incidental findings at surgery or necropsy in four men and three women whose ages ranged from 48 to 79 years (mean 63 7 years). Four were found in the right lobe and three in the left. Six were subcapsular and only one deep in the parenchyma, with sizes
Kimura's disease is a chronic inflammatory disorder of unknown etiology, presenting usually as painless subcutaneous swellings in the head and neck region or in the salivary glands. The cytologic features of fine-needle aspirates of eight cases of Kimura's disease were studied with reference to the histologic appearance of the subsequent surgical specimens. In the cytologic smears, the prominent feature was the presence of significant numbers of eosinophils in a background of lymphoid cells. Fragments of collagenous tissue and Warthin-Finkeldey polykaryocytes occasionally were seen. In the cell block, vascular proliferation and fibrosis were useful features, providing further support to the diagnosis. The constellation of these features is characteristic of Kimura's disease and should suggest this diagnosis in the appropriate clinical setting. For initial diagnosis, excisional biopsy is important for the exclusion of malignant lymphoma, histiocytosis X, angiolymphoid hyperplasia with eosinophilia and other reactive lymphadenopathies. Nonetheless, fine-needle aspiration cytology may be valuable in the diagnosis of recurrent lesions of Kimura's disease and may spare the patient from repeated biopsies.
Brief reports 425 (Chaudary et al. 1986). The mucus-containing cells d o not seem to correspond to any normal embryological elements, but their presence further demonstrates the ability of mammary epithelium to produce abundant mucin under certain circumstances, especially manifest in mucinous and signet ring cell carcinomas.
ReferencesCHAUDARY MA, MILLIS RR, LANE EB, MILLER NA. Paget's disease of the nipple: a ten year review including clinical, pathological, and immunohis-tochemical findings. Breast Cancer Rex Treor. 1986; 8; 139-146. KOWAND L, VERHULST LA, COPELAND CM, BOSE B. Epidermal cyst of the breast. Can. Med Assoc. MENV~LLE JG. Simple dermoid cysts of the breast. Ann Surg. 1936; 103; 49-56. SALM R. Epidermoid metaplasia in mammary fibroadenoma with formation of keratin cysts. J. Pathol. Bacteriol. 1957; 74; 221-222. SALM R. Massive epidermoid metaplasia with keratin cyst formation in a giant fibro-adenoma ofbreast.
Leiomyoblastomas are rare tumors, and there have been few reports on their fine-needle aspiration (FNA) cytologic morphology. We herein describe the FNA features of a gastric leiomyoblastoma with subcutaneous metastasis. The cells had eosinophilic cytoplasm and oval eccentric nuclei, occasionally with intranuclear cytoplasmic inclusions. An organoid pattern was obvious in cell block sections. The tumor was positive for vimentin but negative for desmin, S-100 protein, and the common epithelial markers. The histogenesis is discussed, as are reasons why this tumor is better termed epithelioid mesenchymal tumor.
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