This study is a family survey based on a typical patient with seborrhoeic keratosis (SK). Family members comprised 47 people of four generations, including 22 affected members (12 males and 10 females). The 17 people of the fourth generation were aged less than 26 years old. The proband in this study had typical clinical manifestations and pathology of SK, and all affected members of the family had characteristic skin rash that was easy to be identified. The pattern is consistent with autosomal dominant inheritance and SK is indicated to have a certain age onset.

Seborrheic dermatitis (SD) has no diagnostic criteria and its etiology remains unknown. SD is distributed in the areas rich in sebaceous glands. Initially, MALASSEZIA FURFUR was thought to be the causing agent. Currently, SD is thought as not being proportional to the mean yeast count, but rather as an abnormal host immune response to the yeasts on the skin. There are a variety of topical and systemic antifungal agents available as a remedy. Corticosteroids and ultraviolet B are also used as treatment.