Five Schiff bases containing a thiadiazole moiety have been used as poly(vinyl chloride) photostabilizers at low concentrations. The efficiency of Schiff bases as photostabilizers was investigated using various techniques, for example, the changes in poly(vinyl chloride) infrared spectra, molecular weight, chain scission quantum yield, and surface morphology were monitored upon irradiation with an ultraviolet light. Evidently, all the additives used inhibited poly(vinyl chloride) photodegradation at a significant level. The most efficient Schiff base exhibited a high level of aromaticity and contained a hydroxyl group. It seems possible that such photostabilization could be due to the direct absorption of ultraviolet radiation by the additives. In addition, Schiff bases could act as radical scavengers and proton transfer facilitators to stabilize the polymeric materials.

In this study, the new azetidinones were synthesized from Schiff bases 2(a-j) that derived from amoxicillin (1) on treatment with chloroacetyl chloride in presence of triethylamine gave azetidinone 3(a-j). The structure of these compounds have been elucidated on the basis of their physical and spectral. Azetidinone  compounds were also screened for  their antibacterial activity against some bacterial species using amoxicillin as standard.

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