A clinical study was performed to evaluate the diagnostic methods for ovarian cysts (OC), and to determine the metabolic profiles of animals with OC in the region of Mitidja in the North of Algeria. A total of 504 non-pregnant lactating cows were used in this study. Ultrasonography was performed by EXAGO scanner and was combined with assessment of serum P4. Biochemical serum parameters were assayed by spectrophotometry and insulin and cortisol serum measurement was performed by electrochemiluminescence. The results showed an overall incidence of 11.9% of OC. The incidence of OC was higher among cows in third lactation. Holstein breed was the most affected by OC compared with other breeds (P<0.001). There were no effects of average BCS (Body Condition Scoring) and milk production on the incidence of OC (P>0.05). OC were single in 91% of cases. They were found mainly on the right ovary (66.66%). Seasonality had a significant influence on incidence rate of OC with higher incidence rates during winter and spring (71.66%); while, 28.33% of OC were detected during the summer and autumn (P<0.05). OC were associated with low serum concentrations of glucose, insulin and urea as well as high levels of cortisol. Ultrasound examination and progesterone assays were proposed as the most effective diagnostic combination to diagnose OC. In conclusion, in addition to hormonal imbalances, metabolic disorders are involved in the formation and/or persistence of OC. Therefore, the use of metabolic indicators in understanding and exploration of OC is of great interest. Keywords: Cow, Ovarian cyst, Metabolic profile, Ultrasonography Sütçü İneklerde Ovaryum Kistlerinin Tanısı ve Metabolik Profili Üzerine Bir Çalışma ÖzetOvaryum kistlerinin tanısında kullanılan metotları değerlendirmek ve Cazayir'in kuzeyindeki Mitidja bölgesindeki ovaryum kistli hayvanların metabolik profillerini belirlemek amacıyla klinik bir çalışma gerçekleştirildi. Toplam 504 gebe olmayan laktasyondaki inekler bu çalışmada kullanıldı. EXAGO tarayıcı kullanılarak ultrasonografi uygulandı ve serum P4 verileri ile birlikte değerlendirildi. Biyokimyasal serum parametreleri spektrofotometri ile belirlenirken insülin ve kortizol serum ölçümleri elektrokimyasal görüntüleme ile gerçekleştirildi. Ovaryum kist insidansı %11.9 olarak belirlendi. Ovaryum insidansı üçüncü laktasyondaki ineklerde daha fazla oranda tespit edildi. Diğer türler ile karşılaştırıldığında Holstein ırkında ovaryum kisti daha fazla oranda gözlemlendi (P<0.001). Ovaryum kisti üzerine Vücut Kondisyon Skorunun bir etkisi gözlemlenmedi (P>0.05). Ovaryum kisti, vakaların %91'inde tek taraflı olarak tespit edildi. Kistler çoğunlukla (%66.66) sağ ovaryumda yer almaktaydı. Mevsimin ovaryum kistlerinin ortaya çıkmasında önemli bir etkiye neden olduğu, kış ile ilkbahar aylarında (%71.66) insidansın arttığı yaz ve sonbaharda ise düşük seviyede (%28.33) olduğu belirlendi (P<0.05). Ovaryum kistlerinin düşük glukoz, insülin ve üre ile yüksek kortizol serum konsantrasyonları ile ilişkili olduğu belirlendi. Ult...
Among gynecological tumors, malignant uterine tumor (MUT) is the 6th most common cancer in women and the 15th most common cancer overall. There were approximately 382 069 new cases and 89 929 deaths attributed to this type worldwide in 2018. Therefore, MUT was the second most common gynecological cancer and the fourth leading cause of death due to gynecological cancer in 2018, and is expected to increase the incidence rate by more than 50% globally by 2040. Mortality rates are lowest in Central and South Asia and most of Africa. Survivors of MUT may experience treatment-related issues, including infertility, early onset of menopause, sexual problems, and lower limb lymphedema. Wbuilds its own database from national modeling incidence estimates, using incidence ratios with a sampling method that relies on the calculation of a weighted or simple average of the most popular local rates applied to the population of a few regions or by an approximate estimate based on data provided by health establishments in neighboring countries. While in Algeria, existing statistical and epidemiological data and updated information on the pathology are insuffi cient. The objective of this work is to highlight the importance and the situation of the MUT in this country and to describe the different recent aspects (etiology, diagnostics and treatment) related to the disease.
Cancer is a generic term that groups different types of malignant tumors. Each of them has a specifi c name according to the tissue that gave birth to it. It appears when cells multiply in an uncontrolled manner and take the place of healthy cells. Deaths from cancer are mainly due to damage caused by metastases. This is why it is important to diagnose the disease early, before it spreads in the body. After the diagnosis announcement, cancer management is put in place: it involves several treatments that are articulated throughout the course of care. Cancers have the particularity of reacting differently to treatments. Some types of cancer are best treated with surgery. Others respond better to drugs called chemotherapy. It often happens that several treatments are administered together to ensure the best possible results. Studies have so far focused largely on the tumor cell itself. The new challenge for researchers is now to understand how these cells interact with their immediate environment. What processes do they put in place to escape the immune system or to successfully spread? Understanding these mechanisms could lead to the development of new types of treatment.
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