Citation: Karst SG, Beiglboeck H, Scharinger R, et al. Retinal and choroidal perfusion status in the area of laser scars assessed with swept-source optical coherence tomography angiography. Invest Ophthalmol Vis Sci. 2019;60:4865-4871. https://doi.org/ 10.1167/iovs.19-27977PURPOSE. To evaluate the perfusion status of the retina and choriocapillaris in the area of laser scars on swept-source optical coherence tomography angiography (OCTA) images of eyes previously treated with panretinal photocoagulation (PRP). METHODS.Cross-sectional exploratory analysis of swept-source OCTA images, which were retrospectively reviewed for laser scars. The appearance of the capillary networks in the area of previous laser were evaluated following a three-step grading system (normal/sparse/ missing capillary network). The superficial and deep capillary plexus of the retina and the choriocapillaris were graded separately. RESULTS.A total of 3140 laser scars in 54 eyes of 31 patients (13 female, mean age 57 6 12 years) were included in this analysis. In the retina, 6.8% of the superficial and deep capillary network in the area evaluated appeared normal, 58% and 56% sparse, and 35% and 37% missing. Capillary dropout in the retina was not restricted to the area of prior laser treatment. The choriocapillaris decorrelation signal was either sparse (61%) or completely missing (38%) within the laser scar area. The perfusion of the choriocapillaris appeared normal in the area adjacent to laser scars.CONCLUSIONS. Capillary non-perfusion in the choriocapillaris was found within the laser scar area. Laser treatment seems to cause sustained non-perfusion of choriocapillaris in the area treated.