Objectives This study aimed to determine the risk factors for the occurrence of arrhythmias after either transcatheter or surgical closure of atrial septal defect. Methods This prospective study included 150 patients admitted for transcatheter or surgical closure of atrial septal defect. Transthoracic echocardiography together with a twelve-leads ECG were done during 1 and 3 months follow up. The paired T, chi-square and Logistic regression tests were used to detect any association between any arrhythmias and factors that may affect its occurrence. Results One-hundred and twenty-three patients had percutaneous device closure while the remaining 27 patients had surgical closure. The youngest and oldest of the studied patients being 3 & 50 years old respectively with female (108) over male (42) predominance in incidence. After closure, 8 patients at one month and another 3 patients at three months follow up out of the total 150 patients had supraventricular arrhythmias in the form of frequent premature atrial contractions (6 patients), atrioventricular nodal re-entrant tachycardia (2 patients), and paroxysmal Atrial fibrillation (3 patients). No conduction abnormalities nor ventricular arrhythmias occurred. Multivariate analysis showed that age, P wave dispersion, systolic myocardial velocity of right ventricle, and systolic pulmonary artery pressure were independently associated with the occurrence of atrial arrhythmia after atrial septal defect repair. Conclusion Age, P wave dispersion, Systolic pulmonary artery pressure, and systolic myocardial velocity of the right ventricle are independent risk factors to develop arrythmias in patients after atrial septal defect closure.

Objectives The aim of this study is assessment of persistent functional tricuspid regurgitation in patients with atrial septal defect before and after successful device closure and its relationship to tricuspid valve remodeling. Methods The current study was conducted on 60 patients referred to Tanta University Hospital Cardiology Department with the provisional diagnosis of atrial septal defect secundum type for transcatheter closure from December 2017 to December 2019. All patients were subjected to history taking, clinical examination, 12 lead electrocardiography, plain chest X-ray, full two dimension transthoracic echocardiography (for assessment of tricuspid regurgitation severity) before and at 3, 6 months after transcatheter closure. Results Tricuspid regurgitation was decreased significantly after atrial septal defect closure due to remodeling in the right side. Age, estimated systolic pulmonary artery pressure, right atrium end systolic area, right ventricular end diastolic area, tricuspid valve tenting area and height, tricuspid septal leaflet angle and tricuspid annular diameter were predictors of persistent tricuspid regurgitation after 3 and 6 months of closure. Only estimated systolic pulmonary artery pressure, tricuspid septal leaflet angle and tricuspid annular diameter were independent predictors of persistent tricuspid regurgitation after 3, and 6 months of closure. Conclusion Tricuspid regurgitation significantly improved after transcatheter atrial septal defect closure despite its significance at baseline due to remodeling in right side and tricuspid valve.

In the most recent recommendations of the European Society of Cardiology and European Association of Cardio-Thoracic Surgery, both Optical Coherence Tomography (OCT) and Intravascular ultrasound (IVUS) are classified as class IIa for procedural optimization. In a comparison of OCT and IVUS measurement in the phantom model, OCT data corresponded to the real lumen area of the model, but IVUS readings were inflated and less repeatable.

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Background: The use of drug-eluting stents (DES) resulted in innovative progress in the field of interventional Cardiology. Nowadays, the most common indication for coronary stenting is acute coronary syndromes (ACS) due to the better clinical consequences of PCI compared with conservative management. However, in diabetic patients, there is a large debate in the literature regarding the selection of an optimal drug-eluting stent. Aim: This work aimed to compare short term clinical outcome post-percutaneous Coronary intervention with Everolimus-eluting stents (EES) versus Sirolimus-eluting stents (SES) in diabetic patients presented with ACS. Methods: The present study was carried out on 120 diabetic patients presented with acute coronary syndromes (Non-STEMI, Unstable angina) and divided into 2 groups; group 1 included patients treated with PCI with Everolimus eluting stenting (EES), and group 2 included patients treated with PCI with Sirolimus-eluting stenting (SES). Results: After 6 months of follow-up, the percentages of treated patients who were complicated with sudden cardiac death, congestive heart failure, and planned further PCI were 5%, 6.7%, and 6.7%, respectively in group 1, and were 3.3%, 8.3%, and 10% respectively in group 2. While no acute coronary syndrome or repeated coronary angiography was reported in both groups. In the current study, there was no statistically significant difference between the EES group and the SES group in diabetic patients either during implantation or during 6 months follow up (P-value >0.05). Conclusion: In this current study, both EES and SES are comparable to each other regarding the treatment of ACS in diabetic patients.