Diabetes mellitus (DM) is a very common comorbidity worldwide, and it is associated with a wide variety of complications. Diabetic peripheral neuropathy (DPN) is one of these complications that increases the morbidity and mortality of these patients. Multiple studies indicated that lifestyle modifications are very beneficial for these patients in terms of decreasing the symptoms or preventing the progression of the disease. Therefore, a thorough search was conducted to study and shed light on the effects of lifestyle interventions, such as physical exercise, and pharmacological treatment on DPN. A total of 100 studies were found and 32 were selected based on whether or not they support the aim of the study. It was concluded that lifestyle interventions such as regular exercise, healthy diet and weight loss, which will all in turn improve the patient’s glycemic control, play a major role in controlling the disease and preventing its complications. Moreover, the aim of pharmacological interventions is a 30% reduction in pain intensity, however pharmacological interventions are limited in DPN, up till now the FDA approved only three medications that help in the reduction of the pain intensity. These medications are antidepressant duloxetine, anticonvulsant pregabalin, and the opioid-like analgesic tapentadol.

Background: Traumatic bone cyst (TBC) is defined as a non-neoplastic osseous lesion and is considered as a pseudocyst since it lacks epithelial lining. There is a lack of understanding of the etiology and pathogenesis of this lesion. About 90-95% of TBC cases involve the metaphysis of long bones. This article presented a case of TBC in the mandible. Case Presentation: A 21-year-old male patient was presented with no history of trauma. Intra-oral examination revealed normal soft tissue. The lesion was asymptomatic and the teeth in the affected area responded normally to the vitality test. Orthopantomograph (OPG) showed a well-defined unilocular radiolucent lesion, altered bone trabeculations with slight increased bone density from distal root of tooth # 46 to distal root of tooth # 48, and mild thinning of the inferior mandibular borders. Cone-beam computed tomography (CBCT) showed a well-defined periapical lesion with scalloping border around the roots in same site and inferior alveolar canal was displaced. The patient was draped and prepared for an incisional biopsy. A scant soft tissue and fragment of bony material was sent for histopathological examination to confirm the diagnosis. Microscopic examination of the specimen revealed a fragment of vital trabecular bone surrounded by fibro vascular connective tissue, and areas of hemorrhage were also observed that was managed by surgical curettage. Osseous regeneration was reported after 12 months of follow-up. Conclusion: Swelling of the mandible without symptom in a young patient, with or without a trauma history would rise the suspension of a solitary bone cyst.

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BackgroundCardiovascular diseases (CVDs) and their complications are one of the most common causes of death worldwide. Implantable cardiac assistive devices (CADs) play a significant role in preventing dreadful outcomes, and the complication rate of these implanting procedures is minimal. These cardiac devices require some adaptation and could affect the patients' quality of life psychosocially and financially. This study is aimed to identify the impact of implantable cardiac assistive devices on patients' quality of life in the National Guard Hospital, Jeddah, Saudi Arabia. MethodsThis is an observational cross-sectional questionnaire-based study. It was conducted on patients who underwent cardiac assistive device implantation in National Guard Hospital. The patients were interviewed face-to-face and were requested to fill the Implanted Device Adjustment Scale (IDAS). Descriptive statistics were carried out. Chi-square test for independence was conducted to examine the associations between qualitative variables with the level of significance was taken as p-value <0.05. ResultsThere was a statistically significant association between IDAS score and gender (p=0.03), monthly income (p=0.009), and type of cardiac implantation device (p=0.041). Females with an implantable cardiac defibrillator (ICD) and individuals with low socioeconomic status reported alongside divorced participants have higher IDAS scores, which correlates to worse adjustment. However, most of our patients scored 21-50 in IDAS score, which indicates a mild psychosocial effect after the cardiac assistive device implantation. ConclusionThis study confirmed that most individuals adjust positively to implanted devices. It showed a significant association of gender, type of device, monthly income, and duration. Attention must be drawn to females and divorced patients in regards to psychological and emotional support.