A multiple disk centrifugal pump was analyzed as a blood pump for use in cardiac assistance or as a bridge to transplant device. The original configuration consisted of 6 parallel disks with 0.016 inch spacing between disks. This pump suffered from a degradation of flow with increasing afterload. A study was conducted to analyze flow performance as a function of afterload, preload, and motor speed. Configurations were examined including 4, 5, and 6 disks each with spacings of 0.15, 0.20, and 0.25 inches. Flow rates were examined for variations in afterload from 60-130 mm Hg, in preload from 0-20 mm Hg and for motor speeds of 1,250, 1,500, and 1,750 rpm. Analyses of afterload effects were intended to determine those configurations that produced less flow degradation with increasing afterload. Analyses of motor speed effects were intended to determine any configurations that produced greater flow increases with increasing motor speed. A hemolysis study was also performed. Both plasma free hemoglobin and the index of hemolysis were compared to data reported for other centrifugal blood flow devices. Results indicated that a 5 disk configuration with a 0.15 inch spacing produced optimal flow results with minimal degradation at higher afterloads. No optimal configuration based upon motor speed was indicated. Preload effects on pump performance were minimal. Hemolysis results indicated minimal blood damage with levels below those of many other centrifugal blood pump designs.
Flow patterns in a multiple disk centrifugal pump were analyzed so that the device could be incorporated as a ventricular assist or a bridge-to-transplant device. The pump operates either in pulsatile or steady flow modes with the ability to change modes within a fraction of a second. The pump was tested on a mock circulatory system consisting of an arterial fluid capacitor, a systemic resistor, and a venous capacitor. Arterial volume flow rate, arterial pressure, inlet (venous) pressure, and pump rotation speed are continually monitored. A glycerin/water solution is used as a blood analog. Flow visualization was performed with a 3 mW yellow laser, sheet lens, neutrally buoyant amberlite particles, and both still and motion picture photography. Flow patterns matched theoretical predictions very well; inlet flow spread radially outward through the disk annular spaces while propelled by shear and centrifugal forces.
A multiple‐disk centrifugal pump based on the Tesla Turbine design has been modified for potential use as an artificial ventricle or ventricular assist device. The pump consists of a series of interconnected parallel disks placed within a spiral volute housing. This pump normally operates as a continuous flow device; however, a controller circuit has been developed to also allow for pulsatile operation. Frequency, systolic duration, systolic rise time, and diastolic decay time can be independently controlled to produce a wide range of pulsatile pressures and flows. This pumping system was tested in vitro on a mock circulatory system using a blood analogue. Inlet and outlet pressures, outlet flow, and motor rotations per minute were continually monitored over a wide range of physiologic operating conditions. The disk pump output was compared with that of other artificial ventricles and produced favorable results. Direct experimental comparisons were made with a Harvard Apparatus pulsatile piston pump. Unlike the Harvard pump, the disk pump does not use valves. Rather, a slight forward rotation of the disks is used to offset the adverse diastolic pressure gradient, which avoids backflow through the device.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.