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We describe a case series of imaging findings of 4 patients who underwent spinal dysraphisms repair in utero with novel patch material, cryopreserved human umbilical cord, in our institution. In our study, the prenatal and postnatal magnetic resonance imaging and ultrasound are reviewed and showed cord tethering and syrinx progression in all cases. Our report is the first description of magnetic resonance imaging and ultrasound findings in the context of using this novel patch in severe cases of spinal dysraphisms.

and 25 mm (3.0% vs 1.2%, p<0.001). CL was overall more predictive of PTB in AA women (AUC 0.659 vs 0.629, p¼0.045) ( Figure 1). CL 20 mm was more sensitive but slightly less specific for predicting spontaneous PTB in AA women (sensitivity 11.9% vs 5.1%, p<0.001, specificity 99.0% vs 99.7%, p<0.001). At each measure of CL from 20 to 25 mm, CL was more predictive of spontaneous PTB in AA vs non-AA women. The rate of PTB was higher in AA women at each cutoff; AA women with CL 24 mm had a PTB rate similar to non-AA women with a CL 20 mm (48.5% vs 48.5%) ( Figure 2). CONCLUSION: CL is more predictive of spontaneous PTB in AA than in non-AA women. Spontaneous PTB rates are similar in AA women with CL 24 mm and non-AA women with CL 20 mm. These data suggest that the definition of short CL should be race-based given the difference in PTB risk. Future studies should test the efficacy of interventions at a longer CL threshold in AA women.86 Functional and anatomical integrity of spinal cord after in-utero spina bifida repair using cryopreserved human umbilical cord (HUC) Patch vs. Conventional repair (CR) in a Sheep Model