Sarcomatoid carcinoma is a rare, high-grade epithelial malignancy composed exclusively or predominantly of spindle cells often having features suggestive of epithelial derivation without features indica tive of a specific line of mesenchymal differentiation. Sarcomatous carcinomas occur in diverse locations throughout the body, including the upper respiratory tract, upper and lower digestive tracts, genitourinary tract, breast and thyroid glands, among others. Sarcomatoid carcinoma rarely presents in the pancreas. The current study presents the case of a 41-year-old male with a tumor mass in the uncinate of the pancreas and liver metastases. Histopathology and immunohistochemistry of the liver metastases were confirmatory of metastatic sarcomatoid carcinoma. To the best of our knowledge, only nine cases of pancreatic sarcomatoid carcinoma have been reported in literature.
Numb chin syndrome may be the manifestation of a local dental pathology or secondary to a systemic disease. A systematic physical examination with diagnostic workup is of utmost importance in patients presenting with numb chin syndrome. We report the case of a 58-year-old woman who presented with numb chin syndrome. An orthopantogram and computed tomography of the head revealed osteolytic lesion in the left molar region. Histopathological and immunohistochemical examination confirmed the lesion to be metastatic breast carcinoma. Breast ultrasound scan demonstrated a 1.5 × 1.5-cm lesion in the left breast and fine needle aspiration cytology from the lesion confirmed the diagnosis of breast carcinoma. Bone scan showed multiple bone metastases. She was diagnosed to have numb chin syndrome secondary to bone metastases from breast carcinoma. In view of her disseminated disease status, she was started on palliative hormone therapy (Letrozole) with zoledronic acid. We present this case to highlight the importance of careful evaluation of patients presenting with numb chin syndrome because this may be the only manifestation of a systemic malignancy.
A 57-year-old woman presented with right-sided abdominal pain extending from her back to her right leg for 2week duration. She reported that her pain decreased on lying on her left side and flexing her knees. Physical examination demonstrated local tenderness of right costovertebral angle and a positive psoas sign. A computed tomography (CT) scan demonstrated thin-walled, septated psoas abscess (11 cm × 8 cm × 6 cm) (Figs. 1 and 2). Ultrasound-guided percutaneous aspiration revealed serous fluid and she was started on broadspectrum antibiotics. Microbiological examination did
Lymphoma is the second most common primary malignancy occurring in the head and neck with Diffuse large B cell lymphoma(DLBCL) being the most frequent type. Primary Non-Hodgkin's Lymphoma of the scalp is extremely rare. We are describing a case of the same in a 42 year old lady who presented with a diffuse swelling in the right forehead since 3 months of duration. Imaging showed soft tissue lesion arising from the scalp with diffuse hyperostosis of right parietal bone. Further investigations with CT scan chest, abdomen, and pelvis did not reveal any other evidence of systemic disease. Biopsy of the scalp mass was diagnostic of DLBCL scalp. She was treated with chemotherapy followed by radiation.
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