Introduction: Autopsies are carried out to establish the identity, cause of death, time of death and antemortem or postmortem nature of death. A wide variety of pathological conditions involve the lungs. Aim: To study the prevalence and pattern of lung lesions in autopsy cases, confirmed by histopathological examination. Material and Methods: This is an observational study carried out in the pathology department at tertiary care center. Lung tissues from autopsy cases were preserved in 10% formalin, processed and examined microscopically. A total of 500 cases were studied during a 4 year's period from 2017 to 2020. Results: Among the 507 autopsy cases studied, lung specimen from 7 [1.38%] cases were autolyzed hence excluded from the present study. Out of 500 study cases, 70 cases [13.8%] showed unremarkable histopathology. Wide spectrum of microscopic findings was seen in the rest [84.81%] of the cases. Conclusion: Autopsy remains vital and important complimentary tool in identifying and understanding pulmonary lesions. Histopathological study of lungs at autopsy may reveal various lesions and their relative inputs toward death.
Congenital pulmonary lymphangiectasis [CPL] is a rare, poorly documented disease, characterized by abnormal dilatation of pulmonary lymphatics without lymphatic proliferation. This disease is seen almost exclusively in infancy and early childhood. It can usually be divided into primary [congenital] and secondary forms. The primary form presents in neonates, and the patients mostly die due to the respiratory distress, shortly after birth. Here we present a case of pulmonary lymphangiectasia in an one month old child as incidental finding on autopsy.
Sex cord-stromal tumors with annular tubules (SCTAT) of the ovary are rare. They have two clinicalpresentation forms: the syndromic form which is associated with Peutz-Jeghers syndrome and thenon-syndromic form which is frequently seen in the second or third decades. We describe a 25-year-old patient who underwent exploratory laparotomy. Macroscopically large ovarian mass was24.5×24×8 cm in diameter, encapsulated, congested, and lobulated. On the cut section, it wasgreyish with small cystic and hemorrhagic areas. Microscopically, the tumor mass is composed ofmany simple and complex tubular structures that have eosinophilic PAS-positive hyaline globules inthe center and are surrounded by peripheral palisading of the cells. Finally, the tumor was diagnosedas non-syndromic ovarian SCTAT.
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