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Oral cancer is the 12th most commonly occurring cancer in females and the 6th in males. Oral sub mucous fibrosis (OSMF) considered as one of the high-risk precancerous conditions, linked with areca nut chewing. The aim of present bibliometric analysis was to put forward a summary of countries, universities, authors, journals, and research data related to use of turmeric as a therapeutic consideration in potentially malignant disorders (PMDs) and oral submucous fibrosis (OSMF). Methodology: Studies related to use of turmeric as a therapeutic consideration in PMDs and OSMF published in PubMed indexed journals from 2011 to 2021 were extracted from the Science Citation Index expanded core database. Data and research publications of numerous authors, journals, universities, and countries were retrieved and quantitatively analyzed applying the R-Studio biblioshiny package. The core data set comprised of overall 334 journals, as well as books. 724 documents were recognized. Top 20 PubMed indexed journals were selected which publish the data regarding medicinal properties of turmeric. 20 universities were also analyzed regarding treatment of turmeric. Average years from publication are 4.8 years. Results: A total of 724 documents were extracted. These documents were derived from 2011-2021. The number of documents/publication researches steadily increased from 2011 till 2018. Conclusion: This research includes data of 10 years, therefore, this bibliometric research of contribution of turmeric in oral submucous fibrosis and potential malignant disorders will provide complete knowledge during these years. This will provide an insight for new research projects across the globe.

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Background: Cranioplasty is considered an essential step for restoring defects in the skull, generally due to the esthetic appearance, safety of the brain, or handling the adverse effect of the Trephined Syndrome (TS) or sinking skin flap syndrome. Moreover, many studies saw the unexpected enhancement of cognitive and motor function after cranioplasty. These favorable progressive effects can be helpful in further therapy preparations in association with cranioplasty effects. Nevertheless, the proof is mainly restricted to case studies that do not target comparison between different materials in post-traumatic brain injury (P-TBI) people even though it is helpful but not enough. Objectives: To comparatively evaluate the effect of cranioplasty using autologous bone graft, polymethylmethacrylate (PMMA), titanium, and bone cement on cognitive and functional improvement in patients with P-TBI. Methodology: 40 subjects will be allocated into four groups. Group A (10 using Autologous bone graft) Group B (10 using PMMA), Group C (10 using Titanium), and Group D (10 using Bone cement). Glasgow Coma Scale (GCS) and Mini-Mental State Examination (MMSE) will be used for cognitive improvement. For functional improvement, Muscle power and Barthel index will be used. The data will be compared before and after cranioplasty. Expected Results: Cognitive and functional improvement will be present after cranioplasty. But the effect of cranioplasty using autologous bone graft, polymethylmethacrylate (PMMA), titanium, and bone cement has to be evaluated & compared to assess the patient’s cognitive and functional improvement and provide desired intervention as required. Conclusion: This study will comparatively evaluate the effect of cranioplasty using different prosthetic materials and determine which material is better for patients' cognitive and functional improvement.