Cardiovascular disease is increased in individuals with type 1 or type 2 diabetes mellitus (DM). Left ventricular hypertrophy (LVH), which is an ominous prognostic sign and an independent risk factor for cardiac events, is often present in type 2 DM patients. The aim of our cross-sectional study was to evaluate the prevalence of LVH, and risk factors for its development, in normotensive type 2 diabetic patients without antihypertensive medication. The objectives of the study were to find out the prevalence of high left ventricular mass (LVM) in normotensive type 2 diabetic patients and compare it with nondiabetics and to uncover the risk factors for the development of high LVM in normotensive type 2 diabetic patients. A total of 130 age- and sex-matched subjects were selected (65 cases, diabetic normotensive, and 65 controls, nondiabetic normotensive) and baseline data were collected. LVM and left ventricular mass index (LVMI) were calculated using echocardigraphic parameters and body surface area. LVMI was significantly higher in patients with type 2 DM compared with age-, sex-matched healthy population (104.9 ± 21 vs. 78.5 ± 22.7 g/m2, respectively; P < 0.05). BMI, HbA1c, and duration of diabetes were significantly associated with LVH whereas sexes, age, PPBS, were not.

Our trial demonstrates the superior therapeutic effects of nandrolone in male AWS patients, including the androgen deficient.

The abuse of non dependence producing substances has been rarely reported. However, this can be a significant social problem and it may complicate psychiatric disorders like the anxiety states. We are reporting here, a case of the prolonged abuse of multiple gastrointestinal antibiotics like metronidazole, mebendazole and albendazole. The patient had fortunately not developed any overt toxicity from the overuse of these drugs. He was diagnosed with the generalized anxiety disorder with the anankastic personality disorder. He responded favourably to paroxetine and is being maintained on psychotherapy. As far as we know, this is probably the first report of this kind of abuse from India.