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Objectives: The aims of this study are to evaluate the hematological parameters, type and severity of spectrum of anemia in known anemic cases in adult age group. Methods: This study was carried out in the Department of Pathology, in a tertiary health care center on 1330 cases. The cases were from both indoor and outdoor patients admitted in various wards. The samples for test were collected in EDTA tube. The samples were run in hematology cell counter Sysmex XS-800i for hematology indices and other parameters. Results: The overall prevalence of anemia was 71.58%. Moderate degree of Anemia was the most common followed by mild degree. Anemia was present in 39.92% of men and in 60.08% of women. Microcytic hypochromic anemia is the most common type of anemia in adult, more in reproductive age group indicating iron deficiency as the main cause. It was followed by normocytic normochromic anemia both in men and women. Conclusion: Anemia is a widespread public health problem associated with an increased risk of morbidity and mortality, especially in pregnant women and young children. The prevalence of anemia increases with age and is associated with race, chronic diseases, nutritional deficiencies and other conditions such as infection. A diagnosis of anemia warrants adequate clinical attention, to find out the cause, type, severity and this forms the basis for treatment of anemia. RBC indices provide important guidelines for diagnosis, classification and monitoring the treatment of anemia .

The aim of present work was to evaluate and compare the salivary levels of nitric oxide, vitamin C, Total Sialic acid and GSH in cases of Oral Potentially Malignant Disorders (OPMDs) and Oral Squamous Cell Carcinoma (OSCC) and healthy controls. The mean nitric oxide level was 27.34±5.51 μmol/l in OSCC group, 22.5±2.33 μmol/l in OPMD group and 10.11±0.88μmol/l in control group. The glutathione reductase activity in control patients was found to be 0.0915 U/ml under optimal pH, temperature and Km. In OPMD group, the GR activity was found to be 0.0515 U/ml. Similarly, the activity in the OSCC group was found to be 0.0292 U/ml. The total sialic acid (TSA) in the saliva of control patients was found to be 41.241±5.3312μg/mL. In the case of OPMD patients, it was 64.25±4.33μg/mL and in the OSCC patients it was, 79.60±6.93 μg/mL., The levels of salivary vitamin C and glutathione were significantly reduced and those of nitric oxide and sialic acid were raised in patients having OPMD’s and oral squamous cell carcinoma. The anti-oxidant to oxidant index (AOI) was measured between NO and vitamin C; NO and GSH; total sialic acid and vitamin C and lastly, total sialic acid and GSH. Thus, the findings of the present study indicate that estimation of Vitamin C, NO, GSH and sialic acid can be suitably used and could assist in the early diagnosis of potentially malignant disorders and oral cancer using saliva.

To evaluate the comparability of some of the most common radical scavenging assays using 2,2′-azinobis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS), 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, Ferric reducing power assay (FRAP) & nitric oxide. leaves of traditionally important medicinal plant Ehretia acuminata, used in Chinese herbal medicine were identified & analyzed for their antioxidant capacity, total phenolic and flavonoid content & sun protective factor (SPF). In this study different organic solvents, petroleum ether 40-600 C (PE), chloroform (CH), ethyl acetate (EA), ethanol 99.9% (EOL) & water (AQ) were used for soxhlet exraction of E. acuminata leaves. Among them, ethyl acetate extract exhibited strongest antioxidant activity with IC50 between 99 to 250 μg/ml. Ascorbic acid (AA) used as a standard antioxidant exhibited IC50 25µg/ml. Petroleum ether showed weak free radical scavenging activity with IC50 value between 500 to 770 µg/ml. The ability of protection against UV-B region followed the trend EOL> EA> PE> AQ> CH extract. The result reveals that these natural antioxidant potential of E. acuminata represents a side effect-free alternative to synthetic antioxidants in the food processing industry, in sunscreen formulations and for use in preventive synthetic drugs

Brinjal crops were surveyed for  the  incidence of  mosaic disease in  Devipatan mandal   of  Tarai  region, U.P.  On the  basis  of  symptoms, host  range,  physical properties, sap   transmission, insects transmission different  hosts and   seed  transmissions, three different  virus   isolates were   characterized as  PVY,  TRSV and  TMV