We report the case of a 68-year-old male with alcohol-related cirrhosis, diagnosed with hepatocellular carcinoma (HCC) not eligible for liver transplant. After immunotherapy with atezolizumab associated with bevacizumab, he underwent a successful living donor liver transplantation (LT), not showing disease evidence or graft injury, maintaining clinically and radiologically stable 14 months after surgery. This is a successful report of combined atezolizumab plus bevacizumab being used as a bridge to LT in a patient with HCC, showing an important finding in therapy in patients with unresectable tumors at diagnosis.
Relatamos o caso de um homem de 68 anos, com cirrose hepática de etiologia alcoólica, diagnosticado com carcinoma hepatocelular (CHC) não elegível para transplante hepático. Após imunoterapia com atezolizumabe associado ao bevacizumabe, ele foi submetido a um transplante hepático (TH) de doador vivo com sucesso, não mostrando evidencia de doença ou lesão no enxerto, mantendo-se clínica e radiologicamente estável 14 meses após a cirurgia. Esse é um relato de sucesso da combinação atezolizumabe mais bevacizumabe sendo usados como ponte para o TH em um paciente com CHC, mostrando um achado importante na terapia dos pacientes com tumores irresecáveis ao diagnóstico.
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