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The use of invasive mechanical ventilatory support has been increasingly used in the treatment of respiratory insufficiency, since it replaces the respiratory work while reversing the pathological processes that led to its necessity, allowing the recovery of respiratory function. The critical patient's ventilatory weaning requires a rigorous assessment by qualified professionals to reduce complications and the eventual need for (re) intubation, referring to the design and implementation of rehabilitation nursing programs. The nurse specialist in rehabilitation nursing intervenes in an early, autonomous, and differentiated way, avoiding complications and incapacities, promoting effective ventilatory weaning. This integrative review of the literature made evident the gains obtained in the critical patient undergoing invasive mechanical ventilation and included in an early rehabilitation program, revealing significant impact for both the patient and the hospital institution.

Clearing of the airways in patients undergoing invasive mechanical ventilation (IMV) or non-invasive mechanical ventilation (NIMV) is a fundamental intervention that should be performed regularly, not only to avoid accumulation of secretions, but also to prevent the accumulation of secretions. One of the most relevant interventions in this type of patients is the use of the mechanical insufflator-exsufflator (MI-E), commonly known as cough assist. On the other hand, respiratory functional reeducation (RFR) involves a set of non-invasive procedures that allow the secretion to be released. The efficacy of the RFR associated with the use of MI-E presents gains resulting from this conjugation, namely when the person does not cooperate, when he/she shows a decrease in muscle strength or fails to present an effective cough. The integrative review of the literature has made evident the gains that exist for the person in intensive care, using MI-E associated with airway clearance, ventilation performance, airway permeability, decreased complications, and rate mortality.