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Positive association of its local levels with those in serum further implicates the possibility of widespread systemic effects of this infection.

Aim: Extraction site reconstruction is essential for alveolar ridge preservation, keeping in mind future placement of implants. In an attempt to preserve the alveolar bone and to avoid ridge augmentation prior to implant placement, numerous biocompatible regenerative materials have been used immediately following tooth extraction to fill the socket.Methodology: This article is a pilot trial presenting early trends of the comparative use of two forms of calcium sulfate, i.e. medical grade (Dentogen) ® and nano-crystalline (Nanogen) ® as bone graft materials in immediate extraction sockets of three cases, based on histological and radiological assessments.Results: At the end of 4 months following grafting, the extraction sites in all the three cases revealed no significant difference between the two materials. Radiographic assessment revealed an almost complete graft resorption and replacement with spongy bone with bone density comparable to the surrounding bone. Histopathological assessment revealed that 100% of the bone was vital with 52% trabecular bone and 48% bone marrow. Conclusion:Calcium sulfate both medical grade and nanocrystalline form hold a valid premise for use as regenerative materials in extraction sockets with no significant differences seen between them in this pilot trial.

The concept of immediate pontic placement is surely a viable treatment option and promises an excellent transient esthetic solution for a lost tooth as well as enables good preparation of the extraction site for future prosthetic replacement.