Striae Distensae (SD) are common disfiguring skin conditions having significant psychological impact on affected patients, especially in young healthy women. Management of striae poses a therapeutic challenge. Recently, fractional CO2 laser and microneedling radio frequency have shown to be efficacious in the treatment of SD. However, there is paucity of such studies in Indian population. Hence, we intend to conduct the present comparative study. To compare the efficacy and safety of fractional CO2 laser and Microneedling fractional radiofrequency (MnRF) in the treatment of SD. A total of 30 patients (18-40 years) having SD, attending the out-patient department at the Department Of Dermatology, Venereology and Leprosy, Adichunchanagiri Hospital and Research Centre, B.G. Nagara were alternately allocated into group-A (fractional CO2 group) and group-B (MnRF group). Patients in both the groups received four sequential treatments with an interval of 4 weeks between each session. Clinical assessment of the improvement of striae was done based on Global Improvement Scale (GIS) at the end of 1 month after the last session, by a Side-by-side comparison of Pre-operative photographs. In addition, patients were asked to provide their opinion on improvement of striae using the patient satisfaction Visual Analogue Score (VAS). In our study, at the end of 1 month after the last treatment session, according to GIS, clinical improvement of SD was better in Group B when compared to Group A (p=0.000023), which was statistically significant. Patients in Group B were more satisfied with their treatment than the patients in Group A, according to the patient satisfaction VAS score, which was again found to be statistically significant (p=0.00086).Five patients (33.33%) in Group-A had post-inflammatory hyperpigmentation. In the present study, MnRF was found to be more efficacious and safe than fractional CO2 laser in clinical improvement of striae distensae.

<p>Erythrokeratodermia variabilis (EKV) was first described by Mendes da Costa. It is a rare heterogeneous group of inherited cornification disorders characterized by two distinct types of skin lesions: fixed hyperkeratotic plaques and sharply marginated, pruritic, migratory erythematous lesions. We report a case of EKV in a 44-year-old male patient.</p>

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<p>Purpura fulminans is a rare and commonly fatal syndrome that consists of hemorrhagic infarction of the skin and intravascular thrombosis. Purpura fulminans is commonly associated with streptococcal, staphylococcal and meningococcal infection. Indian tick typhus is a rare cause of purpura fulminans. One of the rare causes of purpura fulminans is Indian tick typhus, which is a type of rickettsial spotted fever caused by <em>Rickettsia conorii</em> and transmitted to humans by <em>Rhipicephalus sanguineus </em>(also called the dog tick). Clinical features of Indian tick typhus include fever, maculopapular rash that begins on the extremities with a centripetal spread, and constitutional symptoms including headache, malaise and conjunctival congestion. Severe cases can progress to multi-organ disease including pulmonary edema, meningoencephalitis, renal failure and cardiogenic shock can occur. Current report present a case of a 48 year old male patient who presented with features of Indian tick typhus which progressed to purpura fulminans and necrotizing fasciitis.</p><p> </p>