The infamous COVID-19 outbreak has left a crippling impact on the economy, healthcare infrastructure and lives of the general working class; with all the scientists determined to find suitable and...

Gold (Au) has emerged as a superior element, because of its widespread applications in electronic and medical fields. The desirable physical, chemical, optical, and inherent enzyme-like properties of Au are efficiently exploited for detection, diagnostic, and therapeutic purposes. Au offers a unique advantage of fabricating gold nanostructures (GNS) having exact physical, chemical, optical, and enzyme-like properties required for the specific biomedical application. In this Review, the emerging trend of GNS for various biomedical applications is highlighted. Some notable structural and chemical modifications achieved for the detection of biomolecules, pathogens, diagnosis of diseases, and therapeutic applications are discussed in brief. The limitations of GNS during biomedical usage are highlighted and the way forward to overcome these limitations are discussed.

The evolution of cancers to resist existing therapeutic strategies has constantly led researchers to design next‐generation therapeutics. Research on nanomedicine holds significant potential in developing newer cancer therapeutics. Nanozymes bearing the properties of enzymes can be promising anticancer agents due to their tunable enzyme‐like properties. In one such approach, a biocompatible cobalt‐single‐atom nanozyme (Co‐SAs@NC) bearing catalase and oxidase‐like activities that function in cascade at the tumor microenvironment has been reported recently. The current highlight discusses this investigation to unveil Co‐SAs@NC's mechanism in tumor cell apoptosis through in vivo studies.