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We demonstrate in vivo three-dimensional (3-D) visualization of crystalline lens sutures in healthy eyes using swept source optical coherence tomography (SS-OCT). Volumetric data sets of the crystalline lenses were acquired and processed to obtain enhanced contrast projection images and to extract suture patterns in both anterior and posterior lens. The results presented different types of the sutures including Y-sutures, simple and complex star sutures. Age-related changes in suture arrangement were characterized quantitatively. Crystalline lens suture imaging with SS-OCT might be a useful tool in fundamental studies on development and ageing of human lens.

In this paper, we present age-related changes in the crystalline lens and investigate which OSD zones are more responsible for changes in the lens’s morphology and transparency with ageing. We present both qualitative image and quantitative data analyses of the findings.

The relation between intraocular forward and back scatter is determined in the study on human subjects of different ages. Optical coherence tomography allows to retrieve quantitative information on back scattering in the eye. Double-pass system allows for the assessment of forward scatter.