Upgrading of reinforcements with suitable combinations in Aluminum-based hybrid metal matrix composites became a key area of research in the current manufacturing era. These advanced materials have enriched Properties like specific strength, wear resistance, and low thermal expansion. With these perceptions, the current research paper was focused on AA-2024/MoS2/Al2O3 HMMCs. Taguchi L18 orthogonal array was adopted to design the experiments. Hybrid composites containing MoS2 and Al2O3 reinforcements were fabricated by the stir casting method. The pin on disk tribometer was used for finding the wear rate and coefficient of friction of prepared composites by considering sliding speed, applied load, and sliding time as wear parameters. Further, the influence of wear parameters on Wear Rate and Coefficient of Friction (COF) was presented. Consequently, the significance of the parameters on wear rate and COF are analyzed by analysis of variance (ANOVA).