In this case report, we discuss the presentation of retinopathy of prematurity in triplets born at 25 + 3 weeks gestational age of whom each had a different birth weight, weight gain and treatment requirements. Triplet A weighed 800 g and his retinopathy of prematurity had resolved with no intervention. Triplet B weighed 630 g at birth and he required bilateral intravitreal ranibizumab injection at 32 + 6 weeks. Triplet C weighed 520 g and required bilateral intravitreal ranibizumab injection at 36 weeks, but after 5 weeks he had recurrence which was treated with bilateral diode laser. Triplet C had the poorest weight gain. The main differences between the triplets are the birth weight and the weight gain. Furthermore, refraction was performed at 10 months; triplet A had a hyperopia of +1.25 spherical equivalent in both eyes, triplet B had mild myopia of −0.25 spherical equivalent and triplet C had a myopia of −3.00 spherical equivalent in the right eye and −2.75 spherical equivalent in the left eye.
This study investigates the decision-making challenges that funders in the United Arab Emirates (UAE) face in selecting the best start-ups to receive high returns and ensure the sustainability of the business ecosystem. Further, it examines the funders' risks while making early-stage investments in innovative businesses. Applying a qualitative methodology, indepth interviews were conducted with 12 funders and analyzed using Nvivo software for deeper insights. The analysis permits understanding the dynamics of the key factors that funders consider to make better decisions on the perfect business to invest in with a higher probability of success. The key elements are based on their intuition, entrepreneurs' commitment, and the business trends the government encouraged. Specifically, government policies and programs supporting particular industries act as signals that affect the decisions made by investors. Further, the study highlights the challenges faced while investing in earlystage innovative enterprises. These include startup sourcing, the dedication of the founding and management teams, market risk-such as competition vs. imitation-, governmental regulation and the discrepancy between anticipated policy outcomes and actual implementation, funding needed to keep the business running, and financing constraints. Specific issues were explored, including the UAE business environment and its orientation in terms of growth and innovation. This research contributes to building up an ecosystem that supports start-up financing, providing lessons and implications to strengthen investors' decision-making processes, and developing a framework for financing policies, schemes, and programs for those seeking to encourage start-ups and foster entrepreneurship and economic growth in the UAE.
Purpose: The purpose of this article is to report various types of maculopathy caused by momentary exposure to a high-power handheld blue laser. Methods: The design included a consecutive case series of 4 patients. Evaluation included a full ophthalmic examination and macular spectral-domain optical coherence tomography. Main outcome measures included an analysis of the types of maculopathy and vitreoretinal pathological features. Results: All patients were young men. The most common setting for injury was accidental at play. The types of maculopathies encountered were a full-thickness macular hole (FTMH) in 4 eyes, a premacular subhyaloid hemorrhage in 5 eyes, premacular sub–internal limiting membrane hemorrhage in 2 eyes, an outer retinal disruption at the fovea in 1 eye, an epimacular membrane in 1 eye, and a schisis-like cavity in 1 eye. Snellen best-corrected visual acuity (BCVA) at presentation ranged from 20/40 to 4/200 (mean, 20/290). Only 4 eyes (29%) improved spontaneously with increase in vision, whereas 10 eyes (71%) required intervention. All 4 FTMHs were closed successfully after pars plana vitrectomy. Final mean BCVA in all cases was 20/35. Conclusions: Exposure to high-power handheld laser devices can cause a variety of maculopathies that can reduce central vision permanently. Although vision may improve spontaneously, most cases require intervention. Unrestricted access to commercially available high-power handheld laser devices is dangerous, and public awareness should be encouraged.
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