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Background: Studies in human immunodeficiency virus (DIV) infected adults have demonstrated association of tutullymphocyte count (TLC) <1200/ mm' and sobsequent disease progression or mortality. The association of other surrogate makers such as haemoglobin (lIb), and erythrocyte sedimentation rate (ESR) with CD4 count and disease progression has also been suggested. This study was carried out tu determine the relationship of CD4-positive T lymphocyte counts with TLC, Hb and ESR in HIVinfected individuals. Methods: The study population comprised of 215 antiretroviral treatment naive HIV-I infected adults. The CD4 positive T cell counts, TLC, Hb and ESR of study participants were measored. Spearman's rank order correlation and Receiver Operating Characteristic were used for statistical analy .... Resolt: The seositivity, specificity, positive and negative likelihood ratios for cut-otT value of TLC

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Both the methods showed an excellent concordance for T-cell γ gene rearrangements, However, the same was not seen in the B-cell receptor rearrangements. This may be because of the small sample size or the inability of consensus V primers to recognize complementary DNA sequences in all of the V segments.