Genomic signal processing (GSP) refers to the use of digital signal processing (DSP) tools for analyzing genomic data such as DNA sequences. A possible application of GSP that has not been fully explored is the computation of the distance between a pair of sequences. In this work we present GAFD, a novel GSP alignment-free distance computation method. We introduce a DNA sequence-to-signal mapping function based on the employment of doublet values, which increases the number of possible amplitude values for the generated signal. Additionally, we explore the use of three DSP distance metrics as descriptors for categorizing DNA signal fragments. Our results indicate the feasibility of employing GAFD for computing sequence distances and the use of descriptors for characterizing DNA fragments.

No abstract

The general framework of this research is the pre-processing of the electroencephalographic (EEG) signals. The goal of this paper is to compare several combinations of wavelet denoising (WD) and independent component analysis (ICA) algorithms for noise and artefacts removal. These methods are tested on simulated EEG, using different evaluation criteria. According to our results, the most effective method consists in source separation by SOBI-RO [1], followed by wavelet denoising by SURE thresholding [2].

No abstract