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BackgroundType 1 diabetes mellitus (T1DM) is one of the most common chronic diseases in children that may be due to micro or macrovascular complications. Diabetic renal disease or nephropathy is a common complication of DM, clinically silent and the only detectable abnormality due to the presence of microalbuminuria.Subjects and methodsThis study was a case–control study. Participants were classified into two groups. The first group included 40 children with T1DM and the second group included 30 matched healthy controls. Serum apelin (APLN), chemerin, cholesterol, and triglycerides (TG) levels were measured for each case. Also, albumin/creatinine ratio was analyzed in random urine sample.ResultsComparison between T1DM patients and controls revealed that serum apelin, chemerin, cholesterol, TG levels, and albuminuria were significantly increased in cases compared to their controls. Significant positive correlations were found between HbA1c% and albuminuria for APLN and chemerin in the diabetic group. Whereas significant negative correlations were found between apelin and glomerular filtration rate (GFR).ConclusionIncreased levels of serum apelin and chemerin in T1DM patients may be considered as promising adipokines for the development of diabetic complication.

BACKGROUND: Adolescence is a phase of rapid growth and increased nutritional needs. It includes the stressful burden of pubertal changes, both physically and psychologically. Moreover, it is associated with the utmost need for independence and identity formation. An adolescent finds a great way to practice taking their own decisions by making personal food choices. But unfortunately, wrong dietary choices lead to unsatisfactory nutritional status. AIM: To investigate the prevalence of six eating behaviours among adolescents. SUBJECTS AND METHODS: A case-control study was conducted on ninety Egyptian adolescents from 10 to 18 years old. Anthropometric measurements were taken. Body Mass Index (BMI) was calculated. The cases were forty-five children with body mass index ≥ 85th percentile. The control group involved forty-five of matched peers with body mass index ˂ 85th centile. A questionnaire form was constructed according to local customs in Egypt. RESULTS: Two unhealthy behaviours were mostly found in our study group. The first and the predominant one was multitasking while eating practised by 92.1% of candidates and showing the equal distribution in both groups. The second was skipping breakfast and was adopted by 51.7% of the study group with a significantly higher distribution in the ˂ 85th centile group. CONCLUSION: Faulty eating is a behaviour encountered in adolescence irrespective to BMI category. Thus, a normal BMI does not reflect healthy dietary behaviours.

Obesity in adolescents show high prevalence specially in developing countries. Although birth order and sib size have been mathematically coupled and in spite of their respective effect on both overweight and obesity, they have not been estimated before separately. Moreover, the educational achievement of parents might have impact on their children’s nutritional status. Objective This study aims to assess how birth order and number of siblings affect adolescent obesity risk and to examine the impact of parent’s education on adolescent obesity, the results will indicate which family members may be prioritized for inclusion in adolescent obesity prevention programs. Methodology A self-administered questionnaire was used to collect data on individuals aged 10 to 18 years old, including sex, age, birth weight, birth order, number of siblings, lifestyle, and parents' educational level by a self-administered questionnaire completed by an adult member of the family, while measurements of subjects’ height and weight were done in the clinic of nutrition and immunity. The CDC's BMI cut-off points were used to classify the subjects as normal (5–84th percentile) and obese (≥ 95th percentile). Results Distribution of the number of siblings was different in both groups as regards BMI but statistically insignificant, we found no statistically significant difference on correlating birth order and number of siblings. Conclusion Adolescent’s BMI were driven by neither the sibling was (younger or older) nor number of their siblings. There was no significant association between parental education and the development of obesity.