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2DSTE and 3DE can discriminate between normal and abnormal echocardiograms and have the potential to detect subclinical LV dysfunction.

Background-Left atrial (LA) size and function reflect left ventricular (LV) hemodynamics. In the present study, we developed a novel method to determine LA circulation transit time (LATT) by MRI and demonstrated its close association with LV filling pressure. Methods and Results-All subjects were prospectively recruited and underwent contrast-enhanced MR dynamic imaging.Mean LATT was determined as the time for contrast to transit through the LA during the first pass. In an invasive study group undergoing clinically indicated cardiac catheterization (nϭ25), LATT normalized by R-R interval (nLATT) was closely associated with LV early diastolic pressure (rϭ0.