A mitochondria-targeted NIR probe based on the FRET mechanism was developed. It shows ultra-large Stokes shifts (460 nm) and emission shifts (285 nm). Furthermore, we also realized the imaging of SO2 in living SKOV-3 cells, zebrafish and living mice which may be useful for understanding the biological roles of SO2 in mitochondria and in vivo.

Numerous SO32−/HSO3− fluorescent probes have been reported based on various mechanisms. However, most probes are constructed from classic dyes such as coumarin, BODIPY, and cyanine. The development of a new...

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