Latar Belakang: Hipertensi merupakan faktor risiko utama terjadinya penyakit kardiovaskuler, stroke, dan gangguan ginjal. Salah satu faktor yang berpengaruh pada tekanan darah adalah asupan. Peningkatan asupan fruktosa dan lemak seringkali dikaitkan dengan kejadian hipertensi. Fruktosa dan lemak memediasi peningkatan tekanan darah melalui stress oksidatif yang dapat menyebabkan vasokontriksi. Buah belimbing wuluh mengandung zat gizi dan antioksidan yang efektif menurunkan tekanan darah. Metode: Penelitian true experimental dengan randomized control groups pre-post design. Dua puluh satu tikus Sprague dawley dibagi menjadi 3 kelompok: 2 kelompok kontrol dan 1 kelompok perlakuan. Kontrol negatif diberi pakan standar, kontrol positif dan perlakuan diberi 66% dan lemak 10%. Sari buah sari buah belimbing wuluh  dengan dosis 2 ml/200gramBB/hari hanya dibrikan pada kelompok perlakuan selama 14 hari.  Pengukuran tekanan darah sistolik dengan metode tail cuff dilakukan pada hari ke 1, 16 dan 30.Hasil: Hasil post test tekanan darah sistolik pada seluruh kelompok mengalami penurunan. Rerata penurunan tekanan darah sistolik kelompok kontrol negatif sebesar 3,76% dan kontrol positif 0,55%. Penurunan terbesar pada kelompok perlakuan yaitu 30,03%. Pemberian sari buah belimbing wuluh mampu menurunkan tekanan darah sistolik secara signifikan (p<0,05).Kesimpulan: Pemberian sari buah belimbing wuluh dengan dosis 2 ml/200gramBB/hari selama 14 hari  berpengaruh terhadap penurunan tekanan darah secara signifikan pada tikus yang diberi pakan tinggi fruktosa dan tinggi lemak.

The high level of ammonia and nitrite is a toxic factor for both poultry and aquaculture animals that directly lead to lower economic benefits. Thus, reducing ammonia and nitrite levels is an essential key for successful culture and is also important to reduce the amount of ammonia and nitrite released into the environment. This study aimed to screen bacteria having a capacity to degrade either ammonia or nitrite in vitro. Five bacterial strains previously isolated from broiler chicken (Gallus gallus domesticus) intestine and pond sediment of Nile Nilapia (Oreochromis niloticus) were used in this study, namely IBP-1, IBP-2, IBP-3, IBP-4, and IBP-5 strains. The screenings were performed using either NH4Cl containing medium or NaNO2 containing medium to determine the ability of bacteria to reduce ammonia or nitrite respectively. The ammonia and nitrite levels were afterwards measured at the beginning (day 0: before bacterial inoculation), 24h (day 1), 48h (day 2), and 72h (day 3) after the addition of 1 ml of the bacterial suspension. The results showed that the five bacterial isolates were able to degrade the ammonia and nitrite content. The greatest reduction of ammonia was achieved by IBP-4 strain (0.00 mg/l), followed by IBP-5 strain (0.04 mg/l), IBP-1 strain (0.05 mg/l), IBP-3 strain (0.14 mg/l) and IBP-2 strain (0.19 mg/l). IBP-1 and IBP-2 strains showed the highest reduction of nitrite levels with values of 0.01 mg/l and 0.02 mg/l after 72h of bacterial inoculation. These results suggest that the five bacterial strains are potentially used for degrading toxic ammonia and nitrite.

The frenulum is a fold of mucous membrane that attaches the lips and cheeks to the alveolar mucosa, gingiva, and underlying periosteum. High frenulum attachment can cause periodontal and esthetic problems, such as gingivitis, gingival recession, and central diastema which require frenectomy. Frenectomy is the complete removal of the frenulum, including its attachment to the alveolar bone, causing a wide wound and triggering bleeding. A 21-year-old female patient who came to the Mataram City Hospital complained that her upper front teeth were not meeting and spaced. This situation makes the patient feel insecure. The patient had no history of systemic disease. OHIS is good and objective examination shows a central diastema due to the attachment of the superior labial frenum which achieves papillary penetration. Management is done by frenectomy with electrosurgery. The patient was very satisfied with the results. Frenectomy using electrosurgery provides good esthetic results and less bleeding.