ChemInform Abstract The aryl isothiocyanates (I) undergo ring closure reaction with 2-chloroethylamine hydrochloride (II) in pyridine to form the N,N'-bis(aryl)-N-(2-thiazolin-2-yl)thioureas (III). The analogues (VII) of (III) are prepared from 2-chloroethyl isothiocyanate (IV) by cyclization with the anilines (V), followed by addition of phenyl isothiocyanate (Ia). Reaction of (VI) with the isocyanates (VIII) results in cyclization to form the thiazolinylureas (IX).
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