Article InfoBackground: Observing ethical principles is a part of nursing occupation and nurses should be aware of the importance of this subject when providing nursing care in order to provide their skills based on occupational ethics. Therefore, this study was conducted with the aim to investigate the relationship between occupational stress and the workplace spirituality with the nurses' occupational ethics through the mediating role of job enthusiasm. Materials and Methods: This was a cross sectional-descriptive study. The study population consisted all man and woman nurses working at hospitals in Zahedan City, Iran. Cluster sampling method was used to select the sample group. A total of 160 nurses were selected as the sample for the study. To collect data, the organizational spirituality questionnaire proposed by Milliman, et al., standard occupational ethics questionnaire by Gregory C. Petty and Expanded Nursing Stress Scale (ENSS) by French et al., and job enthusiasm questionnaire were used. The data were analyzed using path analyzing method. Results: The present study showed that the job enthusiasm variable plays a mediating role between workplace spirituality and occupational stress with the nurses' occupational ethics (P < 0.001). In addition, the positive effect of workplace spirituality (0.277) and negative occupational stress (-0.204) was significant on occupational ethics (P < 0.001). Conclusions:The results of the study, in line with other studies, show that occupational stress and workplace spirituality with impact on job enthusiasm can explain the occupational ethics of nurses.

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