Background: As a destructive factor for the success of athletes, the identification of sports injury helps to prevent and reduce it and is associated with the optimal performance of the athlete. Therefore, the present study aimed to profile musculoskeletal injuries in stone Press (metal shield) and kabbadeh-keshi (iron weight) skills of zurkhaneh (palestra) sports. Methods: In this study, 361 athletes engaged in two zurkhaneh skills were studied in 2019. Data were collected by a questionnaire and analyzed by the Chi-square test at a level of 5% error using SPSS software version 22. Results: The results of the 51 surveyed athletes indicated that the numbers and frequencies of injuries in the metal shield skill were one (5.9%), two (76.5%), and three (17.6%), with an average number of 2.12 ± 0.48 injuries for this skill. Moreover, spasm, sprain, strain, and disc injuries were the most common types of injuries among the stone Press athletes. In the kabbadeh-keshi skill, one (0.18%), two (48.0%), three (0.28%), and four (0.6%) injuries were recorded among 50 athletes examined in this category, with an average number of 22.82 ± 2.82 injuries for athletes in this skill.
Background: Glioblastoma (GBM) is one of the most aggressive tumors, health-threatening, and resistant to available treatment approaches for people worldwide. Objectives: This study aimed to evaluate effects of swimming training and a supplement comprising four nanoliposome herbal extracts in a rat model with mid-brain tumor. Methods: In this experimental study, 56-male-Wistar rats (230 ± 20 g) were divided into eight groups (n = 7): Normal group, model group, model + exe group, model + lipo, model + extract, model + lipo-extract, model + extract-exe, model + lipo-extract + exe. Mid-brain tumor model was induced by injection of the C6 glioma cell line (5 × 105 cell suspension) using stereotaxic techniques in the substantia nigra area of rats. Consumption of nanoformulation of herbals extract (100 mg/kg/day), crude extract (100 mg/kg/day), and swimming training (30 min, 3 days/week) were performed for six weeks. P53, Hras, IL-10, and Casp8 were studied by bioinformatics analysis. We assessed the relative expression of genes in the mid-brain tumor via the quantitative Real-Time PCR (qRT-PCR) method. Beam test and sciatic functional index assessed nerve function and motor coordination. Results: In-silico analysis highlighted substantial genes with significant differential expression compared to healthy status as biomarkers in pathogenesis conditions. The expression level of the P53 and Hras increased with swimming training and nanoliposomes enriched complex complement. Besides, the expression of the IL-10 and Casp8 decreased with swimming training and nanoliposomes enriched complex complement. Conclusions: Our findings show that swimming training and nanoliposome-enriched combined supplements in rats can possibly be considered effective complementary medicine for motor impairment recovery induced by the brain tumor in the substantia nigra area.
Background: Study on the effectiveness of new methods of low back pain treatment is very important due to its high prevalence. There is no consensus on the most effective treatment for low back pain, despite the existence of different treatments options. Objective: This study aims to assess the effect of 8 weeks of dynamic neuromuscular stabilization (DNS) and core stability (CS) exercises on pain, hamstring flexibility, balance, abdominal muscle strength, and quality of life (QoL) in men with chronic low back pain. Methods: Participants were 20 men with non-specific low back pain, randomly divided into two groups of DNS (Age=47.8±9.82 years, BMI=25.8±2.9 kg/m2) and CS (Age=42.4±11.8 years, BMI=28.1±13.1 kg/m2). Subjects performed exercises for 8 weeks. Before and after exercises, their pain, hamstring flexibility, static and dynamic balances, abdominal muscle strength, and QoL were assessed. For data analysis, the paired t-test and analysis of covariance were used, considering a significance level of P<0.05. Results: Both training methods improved pain, abdominal muscle strength and static balance. The CS exercise significantly improved hamstring muscle flexibility, and DNS exercise significantly improved QoL. The comparison between the two methods showed no significant difference in any study variables. Conclusion: Both CS and DNS exercises can be used in designing the interventions for patients with chronic low back pain.
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