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Maxillary advancement by Le Fort I osteotomy has become the standard procedure to restore function and facial esthetics, correct skeletal and occlusal discrepancies, and treat obstructive sleep apnea in patients with facial deformities. Incomplete ossification between the bone segments at the jaw osteotomy site has proven to be a major problem in these patients. There are several studies in the literature that address orthognathic surgery, but only a limited number that discuss the use of graft materials in maxillary osteotomy. Bone grafts were introduced in recent decades in order to promote and improve bone union and prevent the formation of gaps. This study will discuss the results obtained using bone substitutes in orthognathic surgery for maxillary advancement and maxillary repositioning with Le Fort I osteotomy, in a clinical report and a literature review, covering the main indications and specifying the type of material used and the stability of the surgical procedure postoperatively.

The purpose of this article is to describe a clinical case where recombinant human growth hormone (rhGH) associated with Bio-Oss  was used in socket preservation. 53-year-old female patient, ASA I, attended the dental clinic presenting a root fracture of the second upper right premolar. The treatment plan consisted of tooth removal and socket preservation with rhGH and Bio-Oss. After 4 months, a tomography scan was performed before implant placement. At the time of the implant placement, a bone sample was sent for histological analysis. The collected material was analyzed histologically and demonstrated mature bone, with areas of neoformation and deposition of bone matrix and the tomographic aspect was of a hypodense image inside the socket. Socket preservation realized with rhGH associated with Bio-Oss  was able to maintain the three-dimensional dimensions of the sockets, promoting neoformed bone with histological and radiographic features of maturation and was able to reduce the time of treatment.

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