Several cases of albinism, melanism, leucism and piebaldism in mammals have already been reported in the scientific literature. Such genetic mutations are important to be reported, because it can affect the ecological interactions of Pampas Fox individuals with piebaldism, such as predation and mating.Here we report the first case of piebaldism for the Pampas Fox Lycalopex gymnocercus (Carnivora, Canidae), observed in a rural area within the municipality of Bagé,