Saccharomyces paradoxus is the closest known relative of the well-known S. cerevisiae and an attractive model organism for population genetic and genomic studies. Here we characterize a set of 28 wild isolates from a 10-km 2 sampling area in southern England. All 28 isolates are homothallic (capable of mating-type switching) and wild type with respect to nutrient requirements. Nine wild isolates and two lab strains of S. paradoxus were surveyed for sequence variation at six loci totaling 7 kb, and all 28 wild isolates were then genotyped at seven polymorphic loci. These data were used to calculate nucleotide diversity and number of segregating sites in S. paradoxus and to investigate geographic differentiation, population structure, and linkage disequilibrium. Synonymous site diversity is .%3.0ف Extensive incompatibilities between gene genealogies indicate frequent recombination between unlinked loci, but there is no evidence of recombination within genes. Some localized clonal growth is apparent. The frequency of outcrossing relative to inbreeding is estimated at 1.1% on the basis of heterozygosity. Thus, all three modes of reproduction known in the lab (clonal replication, inbreeding, and outcrossing) have been important in molding genetic variation in this species.
The rubber hand illusion (RHI) is a body ownership illusion whereby congruently stroking a fake rubber hand and a subject's hidden hand while observing the rubber hand produces the illusion of them feeling the touch on the rubber hand and experiencing the rubber hand to be part of their own body. The parameters of the RHI have not been fully defined and we describe an approach utilising digital media and technology to examine and establish parameters for this illusion beginning with three experiments: (i) Repeating the original RHI to determine if our test conditions are conducive to producing the classic illusion. (ii) Replacing the original rubber hand with either a static or animated digital image of it displayed on a tablet. (iii) A VR implementation whereby participants see an image of their own hand viewed through a head-mounted display. Measurements of proprioceptive drift (an objective indicator of the feeling of ownership of the rubber hand) corroborated the original RHI and also suggested that a similar phenomenon can occur when the rubber hand was replaced with either a static or animated digital image of it or in a VR condition. Rubber hand illusion, digital media, virtual reality, body ownership illusions.
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