No abstract

of distress and functional impairment. Diagnostic criteria for PTSD include a history of exposure to a traumatic event leading to intense fear and symptoms from each of 3 symptom clusters: intrusive recollections (cluster B), avoidance/numbing (cluster C), and hyperarousal (cluster D). 1 Recent data estimate lifetime PTSD prevalence to be 10.9%, 2 with up to 40% having a chronic form that is prolonged, may be unremitting, and is subject to reactivation upon exposure to stressors. 3 Treatment of PTSD is often complicated by the presence of comorbid anxiety, mood, and substance use disorders as well as somatic diseases. 4,5 Recent scientific advances have elucidated the neurobiology of PTSD, which includes a complex, multifaceted interplay of changes or differences in neuroendocrine systems, brain structure and function, and physiologic reactivity. 5 Pharmacotherapeutic treatment of PTSD has been substantiated by few placebo-controlled trials, with open

No abstract

The results suggest that physiologic assessment may capture long-term effects of terrorism that are not identified by psychometric instruments. The consequences of autonomic reactivity despite emotional resilience years after experiencing trauma are unknown but theoretically could range from facilitating a protective vigilance toward future disasters to more maladaptive avoidance behaviors, somatic symptoms, or medical problems.

The APS Journal Legacy Content is the corpus of 100 years of historical scientific research from the American Physiological Society research journals. This package goes back to the first issue of each of the APS journals including the American Journal of Physiology, first published in 1898. The full text scanned images of the printed pages are easily searchable. Downloads quickly in PDF format.