Background and Aim: Increased oxidative stress has emerged as one of the prime factors in the pathogenesis of periodontitis. Hence, antioxidant therapy may become a promising tool in the treatment of periodontal disease. Uric acid is a major salivary antioxidant, levels of which decrease in periodontitis. The aim of the present study was to investigate the effect of antioxidant therapy on the progression of periodontal disease. Material and Methods: This is a randomized controlled clinical trial conducted among 48 systemically healthy participants having generalized gingivitis with probing depth <3 mm, plaque index (PI) <1, and no bone and attachment loss. Participants were randomly assigned equally (n = 24) into two groups (test and control) using the lottery method. Full mouth scaling and root planing were performed in both the groups and oral hygiene instructions were given. Periodontal assessment at baseline 1 h after scaling and root planing was done with clinical parameters by a single examiner. Test group was prescribed; the commercially available anti-oxidant containing natural lycopene with green tea extract. Sample collection was done for both the groups at baseline and at the 45th day. Results: It was observed that significantly high results were obtained during intra-group comparison for both modified plaque index and sulcus bleeding index from baseline to 45 days. After treatment, a very highly significant increase (P ≤ 0.001) in the test group and significant (P ≤ 0.05) increase in the control group were observed in salivary uric acid levels. Conclusion: Oral lycopene and green tea extract supplementation is positively associated with salivary uric acid levels and plays an important role in the management of gingivitis.

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Objectives: The aim of the study was to evaluate the anti-inflammatory effect of statin medication in chronic periodontitis patients and to compare the change in periodontal probing depth and clinical attachment level using 1.2% atorvastatin (ATV) gel and scaling and root planning (SRP) compared to SRP alone. Materials and Methods: This study was carried out on a sample size of 40 patients with equal male and female ratio between the age group of 40–60 years having chronic periodontitis with a minimum of 20 teeth that were selected for the study. Bilateral quadrants were selected and a split mouth study was conducted. Supragingival scaling was carried out in each patient in one long appointment. The patient was then recalled after 1 week for subgingival SRP. Root planing was carried out in two consecutive visits. Left side of the mouth on the 1st day followed by right side of the mouth on the next day. On the 2nd day, after completion of the root planning, followed by placement of 1.2% ATV gel and finally the Coe Pak was placed in one quadrant which was called the test site. In the other quadrant which was called control site placebo gel was placed and the treated site was covered by the Coe Pak. The recording of clinical parameters (plaque index [PI], gingival index [GI], probing pocket depth, and clinical attachment loss) was done at baseline, 1 month and 3 months. The selected site was sampled for subgingival microflora. The data obtained were subjected to statistical analysis. One-way ANOVA, Tukey’s HSD test, and student t-test were used for intergroup and intragroup comparison. Results: In our study, when intergroup comparison of mean value for PI at baseline, 1 month and 3 months was found to clinically insignificant for control and test groups, while for GI, periodontal pocket depth, and clinical attachment level it was found insignificant at baseline while significant at 1 and 3 months. Similarly, when comparison was made for microbial count it was found clinically insignificant between control and test group at baseline, while significant was noted at 3-month interval. Conclusion: Our study evaluated the anti-inflammatory, osteoconductive and antimicrobial effects of atorvastatin giving significant reduction in PI, GI, PPD and gain in CAL along with significant decrease in the microbial load.

Objectives: With increasing numbers of various periodontal problems one of most frequently encountered is chronic periodontitis. Although the benchmark for treatment is always scaling and root planing, non-invasive adjuncts to SRP in the form of various irrigations have shown promising results. Ozone, one of potent oxygen scavenger, is used in this study as an adjunct to non-surgical periodontal therapy. Materials and Methods: A total of 60 patients with 186 sites were selected with PPD >5 mm, PI >2, GI >2. Scaling and root planing was performed meticulously and on the same day ozonated olive oil irrigation was performed and the healing of gingiva was checked by clinical parameters after 1 month. Results: Statistically significant reduction in PPD, plaque index has been seen at the end of period of 1 month. Conclusion: Use of ozonated olive oil irrigation as an adjunct to scaling and root planning showed good results in reduction of clinical parameters, in patients with chronic periodontitis.

Periodontally accelerated osteogenic orthodontics (PAOO), also known as Wilckodontics, is a clinical procedure that combines corticotomy (a surgical technique in which the bone is cut, perforated, or mechanically altered), particulate bone grafting, and orthodontic force application. By this procedure, the teeth can be made to move through the bone rapidly by means of harnessing and stimulating the innate potential of the bone and utilizing tissue engineering principles. Once the tooth movement gets completed, bone rebuilds around the tooth, thereby reducing the time of orthodontic treatment from years to months. This article aims to present a comprehensive review about PAOO or Wilckodontics.