1. Megakaryocytes can be demonstrated with great frequency in the viscera. 2. Megakaryocytes were present in the lungs in all of 50 autopsies studied. 3. They were next most frequently found in the spleen. 4. The simultaneous occurrence in the various organs, in the absence of extra-medullary hematopoiesis, is roughly related to the concentration in the lungs. 5. Under normal conditions megakaryocytes in small numbers circulate in the blood stream.

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osis. Certainly such a coincidence is possible; however, in reviewing the heretofore published cases and con¬ sidering the reported patients above, we find that the majority were in the third to fifth decades of life at the onset of the convulsive attacks. The onset of "idiopathic" seizures at this age level is remote. Also, familial tenden¬ cies were nonexistent in the reported cases. Electro¬ encephalographic examinations were made in all four of the reported patients above; identical examinations were also made on four patients who had multiple sclerosis without seizures. Three of those who experienced con¬ vulsive discharges had abnormal electroencephalograms, and two of those without seizures had abnormal records. Slow activity of focal origin was the commonest finding in the abnormal records. The electroencephalographic patterns in our patients were not those of idiopathic convulsive disorders.Wilson and MacBride 7 and others have pointed to the relatively small group of patients with disseminated sclerosis who have purely cortical signs and symptoms. These authors further state: "from the neuropathologic standpoint a pure cortical localization of the dissemi¬ nated lesions is not very common, in comparison, that is to say, with the frequent ependymal, periventricular, mesencephalic, pontocerebellar and spinal sites that they