Gated cardiac magnetic resonance (MR) images were obtained in two normal volunteers and 21 adults with a variety of cardiovascular abnormalities. The images were correlated with data from clinical examinations, electrocardiograms, and cardiac catheterization. Gated cardiac images were superior to nongated images. Combined cardiac and respiratory gated images were superior to images obtained with cardiac gating only, but acquisition time was longer. Portions of the coronary arteries were visualized in seven of 23 examinations (30%), and subacute and old myocardial infarcts were seen in five of nine patients (55%) as areas of thinned myocardium. No signal changes were observed in the patients with subacute infarctions or the patient with myocarditis. Coronary atherosclerotic lesions were not visualized in any of the patients. Normal cardiac anatomy (chambers, valves, and papillary muscles) was well visualized. Examples of aortic stenosis and atherosclerosis of the abdominal aorta are shown.
AUTHORS' SYNOPSIS. Renal bloodflow and cardiac output were determined in normal men using single injection radioisotopic techniques. These methods use external monitoring to obviate the discomforts and difficult chemical determinations of older methods. The average cardiac index of 3.36 k 0.35 I./min/ma and the average renal bloodflow of 629 f 70.0 ml.lminlma compare favourably with previously reported values. Measurements of cardiac output and renal blood flow have been relatively complicated and uncomfortable clinical procedures. However, single injection techniques of radioisotopic materials for both determinations are now available and have been simplified by external counting (Pritchard,
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