Nineteen stable left-hemisphere stroke patients with aphasia were evaluated by the Boston Diagnostic Aphasia Examination (BDAE) and the Token Test (TT), and by cranial computed tomography (CT). The types of aphasia included Broca (three patients), Wernicke (four patients), conduction (four patients), transcortical motor (four patients), and global (four patients). The lesions, as localized by CT scan, were superimposed onto five composite lesion localization maps for these five aphasia syndromes. There was good correlation between BDAE aphasia type and lesion localization. On CT scans, the locations of cortical language areas lie in a specific relationship to parts of the ventricular system.
In earlier reports, we commented on the potential of nuclear magnetic reso nance (NMR) for imaging of the brain in children [1, 2]. The high level of graywhite matter contrast available with inversion-recovery (IR) sequences provides a basis for visualization of the normal process of myelination in infancy. Studies of adults have also shown that NMR imaging is sensitive to a variety of pathologic changes, including hemorrhage, infarction, edema, and neoplastic change, which are important in pediatric practice [1,[3][4][5][6][7][8][9][10][11][12][13]. Unlike computed tomography (CT), no hazard is associated with NMR imaging, and, unlike sonography, its applica tion in children is not limited by the closure of the fontanelles. We have now completed NMR examinations of eight normal children and 52 patients up to 13 years of age with a variety of neurologic diseases. The normal appearances and results of these clinical studies are presented.
Subjects and Methods
Approval for this study was obtained from the Research Ethics
The CT findings in both the typical and atypical presentations of the Sturge-Weber syndrome are characteristic if not pathognomonic in most cases. The typical gyriform cortical calcification and cortical atrophy are well demonstrated whether associated with a small or enlarged hemicranium. Contrast enhancement was demonstrated in both cases where contrast medium infusion was performed.
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