Samples of blood and head hair were analyzed for organic and inorganic mercury from a population which consumed large amounts of fish contaminated with methylmercury. Mercury levels in newly formed hair were found to reflect those in blood with the concentration in hair being approximately 300 times that in blood. Organic and inorganic mercury levels were linearly related in both hair and blood samples, with a mean inorganic/organic ration of 0.05 in blood and 0.21 in hair, but individual differences were found to exist. In addition, the total mercury concentration and inorganic/organic ratio in hair remained constant with time. Thus, longitudinal analysis of hair samples can provide a simple and accurate method of monitoring continuing exposure and an estimation of peak blood levels months to years after exposure.
It is gratifying to observe the growing interest in the study of oil-wellspacing. It should always be held in mind that the problem of optimum spacingis to obtain the maximum return of capital per acre drained. This naturallyevolves into a mathematical consideration. As mathematics is the basis of allscience, an effort should be made to develop formulas which involve dataobtainable in the early stages of development.
The first information from a discovery well in a new field would be thecharacter of the sand, rate of initial production of oil and gas, viscosity ofthe oil, rock pressure, etc. Later, from this well, if Herold's theories ofhydraulic, volumetric and capillary controls are accepted, could be determinedthe ultimate production as without interference from drainage by subsequentwell completions, and under which control the well is producing. If it shouldprove to be producing under capillary control, a rough estimate could be madeof its radius of drainage. With but one well, the radius of drainage, or theinterference of drainage of individual wells by close spacing, would beestimated by comparison with similar conditions in other fields in which thedevelopment has progressed sufficiently to furnish the data. A second well thatis spaced sufficiently close so that an interference can be observed after itsultimate production is estimated, will furnish data to develop a desirablespacing of wells which can be inaugurated for that area and which is capable ofproducing a uniform amount of oil under like conditions. In some fields thisarea will be extensive, in others each well location will require an individualstudy.
In 1924, Cutler developed a scheme whereby he determined by tabulation aspacing of oil wells for the maximum return per acre.
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