In this paper, we present the potential of Explainable Artificial Intelligence methods for decision support in medical image analysis scenarios. Using three types of explainable methods applied to the same medical image data set, we aimed to improve the comprehensibility of the decisions provided by the Convolutional Neural Network (CNN). In vivo gastral images obtained by a video capsule endoscopy (VCE) were the subject of visual explanations, with the goal of increasing health professionals’ trust in black-box predictions. We implemented two post hoc interpretable machine learning methods, called Local Interpretable Model-Agnostic Explanations (LIME) and SHapley Additive exPlanations (SHAP), and an alternative explanation approach, the Contextual Importance and Utility (CIU) method. The produced explanations were assessed by human evaluation. We conducted three user studies based on explanations provided by LIME, SHAP and CIU. Users from different non-medical backgrounds carried out a series of tests in a web-based survey setting and stated their experience and understanding of the given explanations. Three user groups (n = 20, 20, 20) with three distinct forms of explanations were quantitatively analyzed. We found that, as hypothesized, the CIU-explainable method performed better than both LIME and SHAP methods in terms of improving support for human decision-making and being more transparent and thus understandable to users. Additionally, CIU outperformed LIME and SHAP by generating explanations more rapidly. Our findings suggest that there are notable differences in human decision-making between various explanation support settings. In line with that, we present three potential explainable methods that, with future improvements in implementation, can be generalized to different medical data sets and can provide effective decision support to medical experts.

Recent efforts in multi-domain learning for semantic segmentation attempt to learn multiple geographical datasets in a universal, joint model. A simple fine-tuning experiment performed sequentially on three popular road scene segmentation datasets demonstrates that existing segmentation frameworks fail at incrementally learning on a series of visually disparate geographical domains. When learning a new domain, the model catastrophically forgets previously learned knowledge. In this work, we pose the problem of multi-domain incremental learning for semantic segmentation. Given a model trained on a particular geographical domain, the goal is to (i) incrementally learn a new geographical domain, (ii) while retaining performance on the old domain, (iii) given that the previous domain's dataset is not accessible. We propose a dynamic architecture that assigns universally shared, domain-invariant parameters to capture homogeneous semantic features present in all domains, while dedicated domain-specific parameters learn the statistics of each domain. Our novel optimization strategy helps achieve a good balance between retention of old knowledge (stability) and acquiring new knowledge (plasticity). We demonstrate the effectiveness of our proposed solution on domain incremental settings pertaining to realworld driving scenes from roads of Germany (Cityscapes), the United States (BDD100k), and India (IDD).

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