The study provides evidence of the influence of beta receptor antagonists on corneal thickness. This effect may be caused by receptor mediated influences on corneal ion and fluid transport. Further studies are needed to show if the increase of corneal thickness after application of topical timolol has clinical importance.
Die Linse kann bei zahlreichen Systemerkrankungen Ver?nderungen aufweisen, die teilweise charakteristisch und damit f?r die Diagnose der Systemerkrankung relevant sein k?nnen (z.?B. Marfan-Syndrom). Die Linsenver?nderungen beinhalten neben der Katarakt als h?ufigste Ver?nderung auch die Linsenresorption oder -kondensation, Ver?nderung der Linsenform und -position sowie Akkommodations- und Refraktionsver?nderungen. Im vorliegenden Beitrag werden kongenitale und fr?hinfantile Linsenver?nderungen (z.?B. bei Trisomie 13 = Patau-Syndrom und Trisomie 18 = Edwards-Syndrom), Linsenver?nderungen im Kindes- und Jugendalter (z.?B. Alport-Syndrom), Linsenver?nderungen im j?ngeren und mittleren Lebensalter (z.?B. Cataracta syndermatotica) und Linsenver?nderungen im h?heren und hohen Lebensalter (z.?B. PEX-Syndrom) beschrieben.
The beginning of ophthalmopathological activities at the University Eye Clinic Tübingen, Germany, can be dated back to the year 1868, as at this time the continuous counting of investigated, ophthalmological specimens was started. So the ophthalmopathological department in Tübingen will be 125 years old in 1993. In a review its history is described with particular regard to the first period and the change in the kind and frequence of diagnoses.
A massively thickened epithelial BM can be occasionally observed in KC but is rare on the whole. It is most likely an unspecific secondary phenomenon and not a prerequisite for KC development. The "inverse cornea guttata" was a unique finding.
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