<b><i>Objective:</i></b> Pre-eclampsia (PE) is a serious disease of pregnancy and one of the major causes of morbidity and mortality for both the mother and baby. This systematic review aims to detect the role of high-sensitivity C-reactive protein (CRP) in the detection of PE. <b><i>Methods:</i></b> Thirty-four articles published between 2001 and 2019 were included in this review. The articles were extracted from OVID Medline and Embase. The study designs of these articles are randomized controlled, cohort, case-control, and cross-sectional studies evaluating CRP as a marker to predict or early diagnose PE. The quality assessment of these articles is made by the modified Quality Assessment of Diagnostic Accuracy Studies 2 tool. Meta-analysis was not done because of clinical and statistical heterogeneity. <b><i>Results:</i></b> A positive association between CRP levels and the development of PE was confirmed in 18 studies. This positive effect was addressed in patients with normal BMI (&#x3c;25 kg/m²) in 3 studies and in overweight patients in 2 studies. One study addressed this positive association in patients with a BMI ranging between 28 and 31 kg/m². Three studies determined a cutoff level of CRP above which a significant risk of PE development should be suspected. These levels ranged between 7 and 15 mg/L. <b><i>Conclusion:</i></b> CRP is a promising cost-effective biomarker that may be used in the prediction of PE. A CRP level higher than 15 mg/L may suggest initiation of low-dose aspirin in low-risk pregnancies.

Objectives: Preeclampsia (P.E) and Eclampsia are hypertensive disorders of pregnancy that complicate 2-8 % of pregnancies globally. Hypertensive disorders of pregnancy constitute one of the leading causes of maternal and perinatal mortality worldwide. The incidence of Preeclampsia in Lebanon was estimated at 2.84%.This study aimed primarily to evaluate the knowledge and practices of Lebanese obstetricians, and secondary to identify the factors associated with these scales. Design: Across-sectional study was conducted between September and December 2020 in obstetricians’ clinics of different healthcare institutions. Methods: Data was collected using a questionnaire based on the recommendations of the National Institute for Health and Care Excellence (NICE) guidelines and American College of Obstetricians and Gynecologists (ACOG) preeclampsia 2020 guidelines. In private clinics, the investigator visited the medical doctor and each doctor agreed to participate in the research, signed the consent form, and filled the distributed questionnaire on his own without any intervention from the investigators. In the hospitals, the questionnaires were distributed to the Obstetrics and Gynecology Department. Results: In this study, 95 doctors were recruited. The practice score of more than half of the 95 doctors (54.7%) is low. The mean of their knowledge score (14.5) is higher than the mean of their practice score (8.5). Almost all doctors have a high knowledge score (96.8%), but more than half of them have poor practice scores (54.7%). A 'in-ear regression showed that the knowledge score decreased for doctors who live in Bekaa. A second linear regression showed that the practice score decreased for doctors who live in Bekaa (p=0.001). However, training on preeclampsia (p<0.001) increased the practice score. A third linear regression showed that the total score decreased for doctors who areliving in Bekaa (p<0.001). However, having a board certificate (p=0.03) and training on preeclampsia (p=0.008) increased the total score. Conclusion: Different continuous medical education activities should be available widely and mandatory for all working doctors to improve their knowledge and practice towards preeclampsia. Preeclampsia can be fatal and every single maternal life should count.