Context: Few researchers have examined shoulder strength in adolescent volleyball athletes despite increasing levels of participation in this age group. Objective: To compare medial and lateral isokinetic peak torque of the rotator cuff among skill levels and between athletes with and without a history of shoulder injury. Design: Cross-sectional design. Setting: The Human Performance Lab and Athletic Training Lab. Patients or Other Participants: Thirty-eight female adolescent club volleyball athletes from 10 to 15 years of age (mean  =  13.02 ± 1.60 years). Main Outcome Measure(s): We measured concentric and eccentric peak torque of the medial and lateral rotators of the shoulder and calculated resultant cocking and spiking ratios based on peak torque values. Results: Athletes at higher skill levels had higher peak torque measurements in concentric and eccentric medial and lateral rotation compared with the athletes at lower skill levels. No differences in peak torque existed between participants with or without an injury history 6 months before the study. Strength ratios did not differ across skill levels, but previously injured participants produced lower eccentric medial rotation to concentric lateral rotation ratios compared with participants without a history of injury (P  =  .02). At the highest skill level, previously injured participants produced lower eccentric lateral rotation to concentric medial rotation ratios compared with participants without an injury history (P  =  .04). Conclusions: Differences in medial and lateral shoulder rotator strength ratios appear to be related more to injury prevalence than to absolute strength. Shoulder dysfunction related to strength ratio deficits also may exist in adolescent female volleyball athletes. Preventive shoulder strengthening programs focused on improving eccentric strength and correcting imbalances between medial and lateral rotators may be warranted for all female adolescent volleyball athletes.

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Recent studies have demonstrated that caffeine can act as an antimutagen and inhibit the cytoxic and/or cytostatic effects of some DNA intercalating agents. It has been suggested that this inhibitory effect may be due to complexation of the DNA intercalator with caffeine. In this study we employ optical absorption, fluorescence, and molecular modeling techniques to probe specific interactions between caffeine and various DNA intercalators. Optical absorption and steady-state fluorescence data demonstrate complexation between caffeine and the planar DNA intercalator acridine orange. The association constant of this complex is determined to be 258.4 +/- 5.1 M-1. In contrast, solutions containing caffeine and the nonplanar DNA intercalator ethidium bromide show optical shifts and steady-state fluorescence spectra indicative of a weaker complex with an association constant of 84.5 +/- 3.5 M-1. Time-resolved fluorescence data indicate that complex formation between caffeine and acridine orange or ethidium bromide results in singlet-state lifetime increases consistent with the observed increase in the steady-state fluorescence yield. In addition, dynamic polarization data indicate that these complexes form with a 1:1 stoichiometry. Molecular modeling studies are also included to examine structural factors that may influence complexation.

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This study assessed reliability of split times obtained by handheld stopwatches (HHSs) compared with electronic timing (ET) during a 200-m sprint. Two HHS timing methods were compared with ET: single-split timers (SST) and multiple-split timers (MST). Twenty-six timers without previous experience were given instruction and completed practice trials until good agreement was achieved between ET and HHS. Trained runners (8 males, 10 females) were timed for each 25-m interval on a standard 200-m course. Repeated-measures analysis of variance and intraclass correlation models were used to determine reliability. A total of 248 split times were analyzed. No significant differences were found between the three timing methods (p > 0.99), and calculated intraclass correlation values were high (0.988). Mean error between SST, MST, and ET (-0.04 +/- 0.24 and -0.05 +/- 0.24 seconds, respectively) indicated faster HHS times, though not significantly. However, absolute errors were considerably larger (0.15 +/- 0.20 and 0.16 +/- 0.19 between SST, MST, and ET, respectively). The HHS-recorded splits were faster than ET in 67.3% of splits and slower in 29.4%. The distribution of errors made the development of a reliable correction factor to convert HHS to ET impossible. It was concluded that on the basis of the small mean error and high intraclass correlations, the use of HHSs may be a viable alternative to ET in collecting group data. However, on the basis of the absolute error between HHS and ET, when high degrees of precision are required, ET should be used, and reliable correction of HHS to ET values is not possible. It was further concluded that HHS times should be reported without attempting correction and interpreted in light of the shortcomings of the HHS method.